알파리포산

Effectiveness of alpha lipoic acid supplementation on biochemical, clinical, and inflammatory parameters in patients with diabetic polyneuropathy: A systematic review and meta-analysis.

1. Diabetes Metab Syndr. 2026 Feb;20(2):103374. doi: 10.1016/j.dsx.2026.103374. Epub 2026 Jan 23. Effectiveness of alpha lipoic acid supplementation on biochemical, clinical, and inflammatory parameters in patients with diabetic polyneuropathy: A systematic review and meta-analysis. Salinas AV(

Effects of alpha-lipoic acid supplementation on cardiometabolic risk factors: A systematic review and dose-response meta-analysis.

2. Nutr Metab Cardiovasc Dis. 2026 Feb;36(2):104370. doi: 10.1016/j.numecd.2025.104370. Epub 2025 Sep 27. Effects of alpha-lipoic acid supplementation on cardiometabolic risk factors: A systematic review and dose-response meta-analysis. Mohammadi S(1), Ashtary-Larky D(2), Alaghemand N(2), Alavi

Efficacy of Alpha Lipoic Acid Supplementation in Sperm Parameters: A Systematic Review and Meta-Analysis of Randomized Trials.

3. Int Braz J Urol. 2025 Jul-Aug;51(4):e20240614. doi: 10.1590/S1677-5538.IBJU.2024.0614. Efficacy of Alpha Lipoic Acid Supplementation in Sperm Parameters: A Systematic Review and Meta-Analysis of Randomized Trials. Pires IZ(1), Gobbo MODS(1), Sudo RYU(2), Milbradt TL(3), Marquardt N Filho(4),

Alpha-lipoic acid on intermediate disease markers in overweight or obese adults: a systematic review and meta-analysis.

4. BMJ Open. 2025 Apr 3;15(4):e088363. doi: 10.1136/bmjopen-2024-088363. Alpha-lipoic acid on intermediate disease markers in overweight or obese adults: a systematic review and meta-analysis. Luo Y(#)(1), Zhang J(#)(1), Guo H(2). Author information: (1)Department of Nursing, West China Hospital

Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials.

5. Int J Vitam Nutr Res. 2024 Dec 27;95(1):36623. doi: 10.31083/IJVNR36623. Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials. Sharifi-Zahabi E(1), Abdollahzad H(2). Author information: (1)Student

Effects of Alpha-Lipoic Acid Supplementation on Weight Loss, Inflammatory, Lipid, and Hematological Levels in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

6. J Ren Nutr. 2025 Mar;35(2):289-299. doi: 10.1053/j.jrn.2024.08.004. Epub 2024 Oct 15. Effects of Alpha-Lipoic Acid Supplementation on Weight Loss, Inflammatory, Lipid, and Hematological Levels in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Randomized Control

Alpha-lipoic acid supplementation affects serum lipids in a dose and duration-dependent manner in different health status.

7. Int J Vitam Nutr Res. 2023 Aug;93(4):352-361. doi: 10.1024/0300-9831/a000732. Epub 2021 Oct 4. Alpha-lipoic acid supplementation affects serum lipids in a dose and duration-dependent manner in different health status. Mahmoudinezhad M(1), Farhangi MA(2). Author information: (1)Student Resear

An updated systematic review and dose-response meta-analysis of the randomized controlled trials on the effects of alpha-lipoic acid supplementation on inflammatory biomarkers.

8. Int J Vitam Nutr Res. 2023 Apr;93(2):164-177. doi: 10.1024/0300-9831/a000702. Epub 2021 Apr 8. An updated systematic review and dose-response meta-analysis of the randomized controlled trials on the effects of alpha-lipoic acid supplementation on inflammatory biomarkers. Vajdi M(1), Mahmoudi

An updated systematic review and dose-response meta-analysis of the effects of α-lipoic acid supplementation on glycemic markers in adults.

9. Nutrition. 2021 Feb;82:111041. doi: 10.1016/j.nut.2020.111041. Epub 2020 Oct 17. An updated systematic review and dose-response meta-analysis of the effects of α-lipoic acid supplementation on glycemic markers in adults. Mahmoudi-Nezhad M(1), Vajdi M(2), Farhangi MA(3). Author information: (1

Alpha-lipoic acid supplementation significantly reduces the risk of obesity in an updated systematic review and dose response meta-analysis of randomised placebo-controlled clinical trials.

10. Int J Clin Pract. 2020 Jun;74(6):e13493. doi: 10.1111/ijcp.13493. Epub 2020 Mar 26. Alpha-lipoic acid supplementation significantly reduces the risk of obesity in an updated systematic review and dose response meta-analysis of randomised placebo-controlled clinical trials. Vajdi M(1), Abbas

Impact of Alpha Lipoic Acid as an Adjuvant Therapy on Inflammation and Fibrosis in Type 2 Diabetic Patients with Ischemic Cardiomyopathy: A Randomized Controlled Trial.

11. J Diet Suppl. 2026;23(1):1-22. doi: 10.1080/19390211.2025.2601020. Epub 2025 Dec 16. Impact of Alpha Lipoic Acid as an Adjuvant Therapy on Inflammation and Fibrosis in Type 2 Diabetic Patients with Ischemic Cardiomyopathy: A Randomized Controlled Trial. Shama AM(1), El-Bassiouny NA(1), Bahn

The role of oral alpha-lipoic acid as an adjuvant antioxidant therapy in diabetic nephropathy among children and adolescents with type 1 diabetes: a randomized controlled trial.

12. J Diabetes Complications. 2026 Jan;40(1):109201. doi: 10.1016/j.jdiacomp.2025.109201. Epub 2025 Oct 18. The role of oral alpha-lipoic acid as an adjuvant antioxidant therapy in diabetic nephropathy among children and adolescents with type 1 diabetes: a randomized controlled trial. Elhenawy

PREVENTION OF PACLITAXEL-INDUCED MOTOR NEUROPATHY OF FIBULAR AND TIBIAL NERVES WITH ALPHA-LIPOIC ACID AND IPIDACRIN HYDROCHLORIDE IN BREAST CANCER PATIENTS.

13. Exp Oncol. 2025 Oct 7;47(2):230-237. doi: 10.15407/exp-oncology.2025.02.230. PREVENTION OF PACLITAXEL-INDUCED MOTOR NEUROPATHY OF FIBULAR AND TIBIAL NERVES WITH ALPHA-LIPOIC ACID AND IPIDACRIN HYDROCHLORIDE IN BREAST CANCER PATIENTS. Holotiuk I(1), Kryzhanivska A(1), Holotiuk S(1), Teren T(1)

l-Carnitine and Alpha-Lipoic Acid Fail to Improve Anaerobic and Aerobic Performance in Trained Cyclists Despite a Reduction in Blood Lactate Concentration.

14. Nutrients. 2025 Jul 4;17(13):2227. doi: 10.3390/nu17132227. l-Carnitine and Alpha-Lipoic Acid Fail to Improve Anaerobic and Aerobic Performance in Trained Cyclists Despite a Reduction in Blood Lactate Concentration. de Rozas A(1), Pérez-Díaz JJ(1), Muros JJ(2), Sánchez-Muñoz C(1), Rufían-Hen

Short-Term Dietary Caffeine Intake for Alleviating Symptoms of Burning Mouth Syndrome: A Randomised Controlled Comparison With Alpha-Lipoic Acid.

15. J Oral Rehabil. 2025 Jul;52(7):969-978. doi: 10.1111/joor.13957. Epub 2025 Mar 14. Short-Term Dietary Caffeine Intake for Alleviating Symptoms of Burning Mouth Syndrome: A Randomised Controlled Comparison With Alpha-Lipoic Acid. Wu C(1), Yuan P(1), Qiu X(1), Liu D(1), Xu Y(1), Xiao Y(1), Zho

A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin.

20. J Postgrad Med. 2024 Oct 1;70(4):191-197. doi: 10.4103/jpgm.jpgm_310_24. Epub 2024 Dec 6. A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on

Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy.

17. Nutrients. 2024 Sep 10;16(18):3045. doi: 10.3390/nu16183045. Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy. Didangelos T(1), Karlafti E

Randomized, double-blind, controlled trial of a combination of alpha-lipoic acid and pregabalin for neuropathic pain: the PAIN-CARE trial.

47. Pain. 2024 Feb 1;165(2):461-469. doi: 10.1097/j.pain.0000000000003038. Epub 2023 Sep 7. Randomized, double-blind, controlled trial of a combination of alpha-lipoic acid and pregabalin for neuropathic pain: the PAIN-CARE trial. Gilron I(1)(2), Robb S(1), Tu D(3), Holden RR(4), Jackson AC(5),

Evaluation of Safety and Efficacy of Add-on Alpha-Lipoic Acid on Migraine Prophylaxis in an Adolescent Population: A Randomized Controlled Trial.

32. J Clin Pharmacol. 2023 Dec;63(12):1398-1407. doi: 10.1002/jcph.2331. Epub 2023 Aug 24. Evaluation of Safety and Efficacy of Add-on Alpha-Lipoic Acid on Migraine Prophylaxis in an Adolescent Population: A Randomized Controlled Trial. Puliappadamb HM(1), Satpathy AK(2), Mishra BR(3), Maiti R(1

Clinical effectiveness of α-lipoic acid, myo-inositol and propolis supplementation on metabolic profiles and liver function in obese patients with NAFLD: A randomized controlled clinical trial.

29. Clin Nutr ESPEN. 2023 Apr;54:412-420. doi: 10.1016/j.clnesp.2023.02.016. Epub 2023 Feb 23. Clinical effectiveness of α-lipoic acid, myo-inositol and propolis supplementation on metabolic profiles and liver function in obese patients with NAFLD: A randomized controlled clinical trial. Tutunc

Neuroprotective evidence of alpha-lipoic acid and desvenlafaxine on memory deficit in a neuroendocrine model of depression.

25. Naunyn Schmiedebergs Arch Pharmacol. 2018 Aug;391(8):803-817. doi: 10.1007/s00210-018-1509-1. Epub 2018 May 7. Neuroprotective evidence of alpha-lipoic acid and desvenlafaxine on memory deficit in a neuroendocrine model of depression. de Sousa CNS(1), Meneses LN(1), Vasconcelos GS(1), da Sil

The protective role of alpha-lipoic acid on long-term exposure of rats to the combination of chlorpyrifos and deltamethrin pesticides.

27. Toxicol Ind Health. 2017 Feb;33(2):159-170. doi: 10.1177/0748233715616553. Epub 2016 Jul 10. The protective role of alpha-lipoic acid on long-term exposure of rats to the combination of chlorpyrifos and deltamethrin pesticides. Uchendu C(1), Ambali SF(2), Ayo JO(3), Esievo KA(4). Author inf

Synergistic ameliorative effects of sesame oil and alpha-lipoic acid against subacute diazinon toxicity in rats: hematological, biochemical, and antioxidant studies.

36. Can J Physiol Pharmacol. 2016 Jan;94(1):81-8. doi: 10.1139/cjpp-2015-0131. Epub 2015 Jul 19. Synergistic ameliorative effects of sesame oil and alpha-lipoic acid against subacute diazinon toxicity in rats: hematological, biochemical, and antioxidant studies. Abdel-Daim MM(1), Taha R(2), Gha

Selective deposition of dietary α-lipoic acid in mitochondrial fraction and its synergistic effect with α-tocoperhol acetate on broiler meat oxidative stability.

1. Lipids Health Dis. 2013 Apr 23;12:52. doi: 10.1186/1476-511X-12-52. Selective deposition of dietary α-lipoic acid in mitochondrial fraction and its synergistic effect with α-tocoperhol acetate on broiler meat oxidative stability. Parveen R, Asghar A, Anjum FM, Khan MI, Arshad MS, Yasmeen A.

Alpha-lipoic acid induces sodium iodide symporter expression in TPC-1 thyroid cancer cell line.

42. Nucl Med Biol. 2012 Nov;39(8):1275-80. doi: 10.1016/j.nucmedbio.2012.08.007. Epub 2012 Sep 18. Alpha-lipoic acid induces sodium iodide symporter expression in TPC-1 thyroid cancer cell line. Choi HJ(1), Kim TY, Ruiz-Llorente S, Jeon MJ, Han JM, Kim WG, Shong YK, Kim WB. Author information:

A combination of melatonin and alpha lipoic acid has greater cardioprotective effect than either of them singly against cadmium-induced oxidative damage.

8. Cardiovasc Toxicol. 2011 Mar;11(1):78-88. doi: 10.1007/s12012-010-9092-9. A combination of melatonin and alpha lipoic acid has greater cardioprotective effect than either of them singly against cadmium-induced oxidative damage. Mukherjee R(1), Banerjee S, Joshi N, Singh PK, Baxi D, Ramachandra

Interactions of the advanced glycation end product inhibitor pyridoxamine and the antioxidant alpha-lipoic acid on insulin resistance in the obese Zucker rat.

45. Metabolism. 2008 Oct;57(10):1465-72. doi: 10.1016/j.metabol.2008.05.018. Interactions of the advanced glycation end product inhibitor pyridoxamine and the antioxidant alpha-lipoic acid on insulin resistance in the obese Zucker rat. Muellenbach EA(1), Diehl CJ, Teachey MK, Lindborg KA, Archule

Efficacy and safety of alpha-lipoic acid supplementation in the treatment of symptomatic diabetic neuropathy.

45. Diabetes Educ. 2007 Jan-Feb;33(1):111-7. doi: 10.1177/0145721706297450. Efficacy and safety of alpha-lipoic acid supplementation in the treatment of symptomatic diabetic neuropathy. Foster TS(1). Author information: (1)University of Medicine and Dentistry of New Jersey, Graduate Program in

Alpha lipoic acid inhibits human T-cell migration: implications for multiple sclerosis.

18. J Neurosci Res. 2004 Nov 1;78(3):362-70. doi: 10.1002/jnr.20255. Alpha lipoic acid inhibits human T-cell migration: implications for multiple sclerosis. Marracci GH(1), McKeon GP, Marquardt WE, Winter RW, Riscoe MK, Bourdette DN. Author information: (1)Portland Veterans Affairs Medical Cente

In vitro neuroprotection against oxidative stress by pre-treatment with a combination of dihydrolipoic acid and phenyl-butyl nitrones.

16. Neurotox Res. 2003;5(4):265-72. doi: 10.1007/BF03033384. In vitro neuroprotection against oxidative stress by pre-treatment with a combination of dihydrolipoic acid and phenyl-butyl nitrones. Koenig ML(1), Meyerhoff JL. Author information: (1)Division of Neurosciences, Walter Reed Army Insti