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Astragaloside IV Supplementation Promotes A Neuroprotective Effect in Experimental Models of Neurological Disorders: A Systematic Review.

1. Curr Neuropharmacol. 2019;17(7):648-665. doi: 10.2174/1570159X16666180911123341. Astragaloside IV Supplementation Promotes A Neuroprotective Effect in Experimental Models of Neurological Disorders: A Systematic Review. Costa IM(1), Lima FOV(1), Fernandes LCB(1), Norrara B(1), Neta FI(1), Alves

Early intervention improves clinical responses to seasonal allergic rhinitis by stimulation in sphenopalatine ganglion (Xinwu acupoint).

2. J Tradit Chin Med. 2023 Aug;43(4):787-794. doi: 10.19852/j.cnki.jtcm.20230524.001. Early intervention improves clinical responses to seasonal allergic rhinitis by stimulation in sphenopalatine ganglion (Xinwu acupoint). Yuhao G(1)(2), Liangran H(3), Lei Z(4), Wei Y(5), Lixia H(1), Wei L(3), Y

Astragaloside IV potentiates cisplatin sensitivity in triple-negative breast cancer via STING signaling pathway activation.

3. Phytomedicine. 2025 Nov 25;148:157330. doi: 10.1016/j.phymed.2025.157330. Epub 2025 Sep 24. Astragaloside IV potentiates cisplatin sensitivity in triple-negative breast cancer via STING signaling pathway activation. Bai B(1), Zhang L(1), Zhang Y(2), Yue R(2), Lu Y(1), Shi R(2), Zhou Q(3). Au

Evaluation of drug interactions of Saposhnikoviae Radix and its major components with astragaloside IV and paeoniflorin using in vitro and in vivo experiments.

4. J Chromatogr A. 2024 May 24;1723:464716. doi: 10.1016/j.chroma.2024.464716. Epub 2024 Feb 3. Evaluation of drug interactions of Saposhnikoviae Radix and its major components with astragaloside IV and paeoniflorin using in vitro and in vivo experiments. Wang QY(1), Liu SY(2), Yu DH(2), Chen PP

Determination of vericiguat in rat plasma by UPLC-MS/MS and its application to drug interaction.

5. J Chromatogr A. 2023 Oct 25;1709:464401. doi: 10.1016/j.chroma.2023.464401. Epub 2023 Sep 19. Determination of vericiguat in rat plasma by UPLC-MS/MS and its application to drug interaction. Ding C(1), Guo C(1), Fang L(1), Li Y(1), Wang Z(2), Dong Z(3). Author information: (1)National Clinic

Implications for herbal polypharmacy: coumarin-induced hepatotoxicity increased through common herbal phytochemicals astragaloside IV and atractylenolide I.

6. Toxicol Mech Methods. 2022 Oct;32(8):606-615. doi: 10.1080/15376516.2022.2057267. Epub 2022 Mar 30. Implications for herbal polypharmacy: coumarin-induced hepatotoxicity increased through common herbal phytochemicals astragaloside IV and atractylenolide I. Britza SM(1), Musgrave IF(1), Byard

Effects of Astragaloside IV on the Pharmacokinetics of Metoprolol in Rats and its Mechanism.

7. Curr Drug Metab. 2022;23(2):131-136. doi: 10.2174/1389200223666220128143133. Effects of Astragaloside IV on the Pharmacokinetics of Metoprolol in Rats and its Mechanism. Shi Z(1)(2)(3), Jiang J(1), Zhao D(1)(3), Xie B(1), Li Y(4), Yu C(1)(2)(3). Author information: (1)College of Pharmacy, Cho

Effects of puerarin on the pharmacokinetics of astragaloside IV in rats and its potential mechanism.

8. Pharm Biol. 2020 Dec;58(1):328-332. doi: 10.1080/13880209.2020.1746362. Effects of puerarin on the pharmacokinetics of astragaloside IV in rats and its potential mechanism. Zhang H(1), Song J(2), Dai H(3), Liu Y(2), Wang L(4). Author information: (1)Department of Ophthalmology, Affiliated Hos

Astragaloside IV enhances cisplatin chemosensitivity in hepatocellular carcinoma by suppressing MRP2.

9. Eur J Pharm Sci. 2020 May 30;148:105325. doi: 10.1016/j.ejps.2020.105325. Epub 2020 Apr 4. Astragaloside IV enhances cisplatin chemosensitivity in hepatocellular carcinoma by suppressing MRP2. Qu X(1), Gao H(1), Zhai J(1), Sun J(1), Tao L(1), Zhang Y(1), Song Y(2), Hu T(3). Author informati

Influence of astragaloside IV on pharmacokinetics of triptolide in rats and its potential mechanism.

10. Pharm Biol. 2020 Dec;58(1):253-256. doi: 10.1080/13880209.2019.1702705. Influence of astragaloside IV on pharmacokinetics of triptolide in rats and its potential mechanism. Gao J(1), Zeng X(1), Zhao W(2), Chen D(1), Liu J(3), Zhang N(3), Duan X(4). Author information: (1)Department of Image,

Astragaloside IV Synergizes with Ferulic Acid to Alleviate Hepatic Fibrosis in Bile Duct-Ligated Cirrhotic Rats.

11. Dig Dis Sci. 2020 Oct;65(10):2925-2936. doi: 10.1007/s10620-019-06017-3. Epub 2020 Jan 3. Astragaloside IV Synergizes with Ferulic Acid to Alleviate Hepatic Fibrosis in Bile Duct-Ligated Cirrhotic Rats. Zhao XM(1), Zhang J(2), Liang YN(1), Niu YC(3). Author information: (1)The Institute of

P-glycoprotein Inhibitor Tariquidar Potentiates Efficacy of Astragaloside IV in Experimental Autoimmune Encephalomyelitis Mice.

12. Molecules. 2019 Feb 3;24(3):561. doi: 10.3390/molecules24030561. P-glycoprotein Inhibitor Tariquidar Potentiates Efficacy of Astragaloside IV in Experimental Autoimmune Encephalomyelitis Mice. Zhang W(1), Liu M(2), Yang L(3), Huang F(4), Lan Y(5), Li H(6), Wu H(7), Zhang B(8), Shi H(9), Wu X

Astragalus membranaceus Extract as a Botanical Ingredient for Pigmentary and Anti-Aging Skincare: A Systematic Review.

13. J Drugs Dermatol. 2026 Jan 1;25(1):88-92. doi: 10.36849/JDD.9157. Astragalus membranaceus Extract as a Botanical Ingredient for Pigmentary and Anti-Aging Skincare: A Systematic Review. Jackson S, Waibel JS, Park L. BACKGROUND: Skin aging results from intrinsic and extrinsic factors, includin

Research progress of bioactive compounds of Traditional Chinese medicine in the treatment of myocardial fibrosis-related signaling pathways.

14. J Ethnopharmacol. 2026 Jan 30;355(Pt B):120694. doi: 10.1016/j.jep.2025.120694. Epub 2025 Oct 3. Research progress of bioactive compounds of Traditional Chinese medicine in the treatment of myocardial fibrosis-related signaling pathways. Li Q(1), Liu A(1), Ren C(1), Zhi X(2), Wang X(3), Lu W

Molecular mechanisms of astragaloside-IV in hepatocellular carcinoma therapy: a systematic review.

15. BMC Cancer. 2025 Sep 1;25(1):1407. doi: 10.1186/s12885-025-14758-w. Molecular mechanisms of astragaloside-IV in hepatocellular carcinoma therapy: a systematic review. Gao X(1)(2), Hao W(2)(3), Wang Y(1), Wu X(2)(3), Zhu F(1), Zhang Y(4). Author information: (1)School of Basic Medical Science

Exploring Astragaloside IV in Ischemic Heart Disease: A Comprehensive Systematic Review and Meta-Analysis of Preclinical Cardiotoxicity Models.

19. J Biochem Mol Toxicol. 2025 Jul;39(7):e70365. doi: 10.1002/jbt.70365. Exploring Astragaloside IV in Ischemic Heart Disease: A Comprehensive Systematic Review and Meta-Analysis of Preclinical Cardiotoxicity Models. Greeny A(1), Viswanatha GL(1), Shenoy RR(1), Hanumanthappa S(2), Chellappan DK

Research progress of effective components of traditional Chinese medicine in intervening apoptosis of renal tubular epithelial cells in diabetic kidney disease.

7. J Ethnopharmacol. 2025 May 28;348:119874. doi: 10.1016/j.jep.2025.119874. Epub 2025 Apr 23. Research progress of effective components of traditional Chinese medicine in intervening apoptosis of renal tubular epithelial cells in diabetic kidney disease. Gong YX(1). Author information: (1)Hei

Anti-fibrosis effect of astragaloside IV in animal models of cardiovascular diseases and its mechanisms: a systematic review.

17. Pharm Biol. 2025 Dec;63(1):250-263. doi: 10.1080/13880209.2025.2488994. Epub 2025 Apr 22. Anti-fibrosis effect of astragaloside IV in animal models of cardiovascular diseases and its mechanisms: a systematic review. Zhang S(1), Li S(1), Li X(1), Wan C(1), Cui L(1), Wang Y(1). Author informa

Intra-myocardial hemorrhage and cardiac microvascular injury in ischemia/reperfusion. A systematic review of current evidences.

44. Curr Probl Cardiol. 2025 Jan;50(1):102918. doi: 10.1016/j.cpcardiol.2024.102918. Epub 2024 Nov 5. Intra-myocardial hemorrhage and cardiac microvascular injury in ischemia/reperfusion. A systematic review of current evidences. Zavadovsky KV(1), Ryabov VV(2), Vyshlov EV(2), Mochula OV(1), Siro

The potential molecular pathways of Astragaloside-IV in colorectal cancer: A systematic review.

15. Biomed Pharmacother. 2023 Nov;167:115625. doi: 10.1016/j.biopha.2023.115625. Epub 2023 Oct 2. The potential molecular pathways of Astragaloside-IV in colorectal cancer: A systematic review. Ziyang T(1), Xirong H(2), Chongming A(3), Tingxin L(4). Author information: (1)Department of Health M

Renal protective effects of astragaloside IV, in diabetes mellitus kidney damage animal models: A systematic review, meta-analysis.

48. Pharmacol Res. 2020 Oct;160:105192. doi: 10.1016/j.phrs.2020.105192. Epub 2020 Sep 15. Renal protective effects of astragaloside IV, in diabetes mellitus kidney damage animal models: A systematic review, meta-analysis. Zhou XT(1), Zou JJ(1), Ao C(2), Gong DY(3), Chen X(4), Ma YR(5). Author