베르베린 (LDL)

Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.

1. Drugs. 2023 Apr;83(5):403-427. doi: 10.1007/s40265-023-01841-4. Epub 2023 Mar 21. Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials. Blais JE(1)(2), Huang X(1), Zhao JV(3).

Protective effect of berberine in diabetic nephropathy: A systematic review and meta-analysis revealing the mechanism of action.

2. Pharmacol Res. 2022 Nov;185:106481. doi: 10.1016/j.phrs.2022.106481. Epub 2022 Oct 3. Protective effect of berberine in diabetic nephropathy: A systematic review and meta-analysis revealing the mechanism of action. Hu S(1), Wang J(2), Liu E(3), Zhang X(4), Xiang J(5), Li W(6), Wei P(7), Zeng

A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults.

3. Pharmacol Res. 2022 Sep;183:106402. doi: 10.1016/j.phrs.2022.106402. Epub 2022 Aug 18. A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults. Osadnik T(1), Goławski M(1), Lewandowski P(1), Morze J(2), Osadnik K(1), Pawlas N(1), Lejawa M(1), Jakubiak G

Original Research: The Effects of Red Yeast Rice Supplementation on Cholesterol Levels in Adults.

4. Am J Nurs. 2017 Aug;117(8):46-54. doi: 10.1097/01.NAJ.0000521973.38717.2e. Original Research: The Effects of Red Yeast Rice Supplementation on Cholesterol Levels in Adults. Peng D(1), Fong A, Pelt AV. Author information: (1)Diane Peng is a family nurse practitioner (FNP) at Temple Physicians

The effects of a nutraceutical combination on plasma lipids and glucose: A systematic review and meta-analysis of randomized controlled trials.

5. Pharmacol Res. 2016 Aug;110:76-88. doi: 10.1016/j.phrs.2016.04.021. Epub 2016 May 6. The effects of a nutraceutical combination on plasma lipids and glucose: A systematic review and meta-analysis of randomized controlled trials. Pirro M(1), Mannarino MR(2), Bianconi V(2), Simental-Mendía LE(3

Effects of a nutraceutical combination containing berberine (BRB), policosanol, and red yeast rice (RYR), on lipid profile in hypercholesterolemic patients: A meta-analysis of randomised controlled trials.

6. Clin Investig Arterioscler. 2016 Jul-Aug;28(4):178-87. doi: 10.1016/j.arteri.2016.03.002. Epub 2016 Apr 28. Effects of a nutraceutical combination containing berberine (BRB), policosanol, and red yeast rice (RYR), on lipid profile in hypercholesterolemic patients: A meta-analysis of randomise

The efficacy and safety of berberine in combination with cinnamon supplementation in patients with type 2 diabetes: a randomized clinical trial.

7. Eur J Nutr. 2025 Feb 25;64(2):102. doi: 10.1007/s00394-025-03618-9. The efficacy and safety of berberine in combination with cinnamon supplementation in patients with type 2 diabetes: a randomized clinical trial. Mansour A(#)(1), Sajjadi-Jazi SM(#)(1), Gerami H(1)(2), Khorasanian AS(1)(3), Mo

Pilot study on the efficacy and safety of berberine in people with metabolic syndrome and human immunodeficiency virus infection.

8. Int J STD AIDS. 2023 Dec;34(14):1042-1052. doi: 10.1177/09564624231196600. Epub 2023 Aug 23. Pilot study on the efficacy and safety of berberine in people with metabolic syndrome and human immunodeficiency virus infection. Ruiz-Herrera VV(1), Navarro-Lara SA(2), Andrade-Villanueva JF(1)(3),

Berberine phospholipid exerts a positive effect on the glycemic profile of overweight subjects with impaired fasting blood glucose (IFG): a randomized double-blind placebo-controlled clinical trial.

9. Eur Rev Med Pharmacol Sci. 2023 Jul;27(14):6718-6727. doi: 10.26355/eurrev_202307_33142. Berberine phospholipid exerts a positive effect on the glycemic profile of overweight subjects with impaired fasting blood glucose (IFG): a randomized double-blind placebo-controlled clinical trial. Rond

The effect of barberry (Berberis integerrima) on lipid profile and systemic inflammation in subjects with cardiovascular risk factors: a randomized controlled trial.

10. BMC Complement Med Ther. 2022 Mar 7;22(1):59. doi: 10.1186/s12906-022-03539-8. The effect of barberry (Berberis integerrima) on lipid profile and systemic inflammation in subjects with cardiovascular risk factors: a randomized controlled trial. Emamat H(1), Zahedmehr A(2), Asadian S(2), Nasr

Combined berberine and probiotic treatment as an effective regimen for improving postprandial hyperlipidemia in type 2 diabetes patients: a double blinded placebo controlled randomized study.

11. Gut Microbes. 2022 Jan-Dec;14(1):2003176. doi: 10.1080/19490976.2021.2003176. Combined berberine and probiotic treatment as an effective regimen for improving postprandial hyperlipidemia in type 2 diabetes patients: a double blinded placebo controlled randomized study. Wang S(1)(2), Ren H(3)

Effect of Berberine on Cardiovascular Disease Risk Factors: A Mechanistic Randomized Controlled Trial.

12. Nutrients. 2021 Jul 26;13(8):2550. doi: 10.3390/nu13082550. Effect of Berberine on Cardiovascular Disease Risk Factors: A Mechanistic Randomized Controlled Trial. Zhao JV(1), Yeung WF(1), Chan YH(2), Vackova D(1), Leung JYY(1), Ip DKM(1), Zhao J(3), Ho WK(4), Tse HF(2)(5), Schooling CM(1)(6)

Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters.

13. Life Sci. 2016 Apr 15;151:50-60. doi: 10.1016/j.lfs.2016.02.046. Epub 2016 Feb 11. Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters. Kou S(1), Han B(1), Wang Y(1), Huang T(2), He K(2), Han Y(1), Zhou X(2), Ye X(

Berberine combined with atorvastatin downregulates LOX‑1 expression through the ET‑1 receptor in monocyte/macrophages.

14. Int J Mol Med. 2014 Jul;34(1):283-90. doi: 10.3892/ijmm.2014.1748. Epub 2014 Apr 22. Berberine combined with atorvastatin downregulates LOX‑1 expression through the ET‑1 receptor in monocyte/macrophages. Chi L(1), Peng L(2), Hu X(3), Pan N(1), Zhang Y(4). Author information: (1)Department o

The anti-diabetic effects and pharmacokinetic profiles of berberine in mice treated with Jiao-Tai-Wan and its compatibility.

15. Phytomedicine. 2013 Jul 15;20(10):780-6. doi: 10.1016/j.phymed.2013.03.004. Epub 2013 Apr 10. The anti-diabetic effects and pharmacokinetic profiles of berberine in mice treated with Jiao-Tai-Wan and its compatibility. Chen G(1), Lu F, Xu L, Dong H, Yi P, Wang F, Huang Z, Zou X. Author info

Berberine and plant stanols synergistically inhibit cholesterol absorption in hamsters.

11. Atherosclerosis. 2010 Mar;209(1):111-7. doi: 10.1016/j.atherosclerosis.2009.08.050. Epub 2009 Sep 4. Berberine and plant stanols synergistically inhibit cholesterol absorption in hamsters. Wang Y(1), Jia X, Ghanam K, Beaurepaire C, Zidichouski J, Miller L. Author information: (1)Institute f

Combination of simvastatin with berberine improves the lipid-lowering efficacy.

17. Metabolism. 2008 Aug;57(8):1029-37. doi: 10.1016/j.metabol.2008.01.037. Combination of simvastatin with berberine improves the lipid-lowering efficacy. Kong WJ(1), Wei J, Zuo ZY, Wang YM, Song DQ, You XF, Zhao LX, Pan HN, Jiang JD. Author information: (1)Department of Pharmacology, Institute

Joint position statement on "Nutraceuticals for the treatment of hypercholesterolemia" of the Italian Society of Diabetology (SID) and of the Italian Society for the Study of Arteriosclerosis (SISA).

21. Nutr Metab Cardiovasc Dis. 2017 Jan;27(1):2-17. doi: 10.1016/j.numecd.2016.11.122. Epub 2016 Nov 22. Joint position statement on "Nutraceuticals for the treatment of hypercholesterolemia" of the Italian Society of Diabetology (SID) and of the Italian Society for the Study of Arteriosclerosis

Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and Berberine on Cardio-Metabolic Risk Factors Among Patients With Type 2 Diabetes Mellitus: A Systemic Review and Bayesian Network Meta-Analysis.

36. Phytother Res. 2025 Dec;39(12):5617-5633. doi: 10.1002/ptr.8431. Epub 2025 May 29. Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and Berberine on Cardio-Metabolic Risk Factors Among Patients With Type 2 Diabetes Mellitus: A Systemic Review and Bayesian Network Meta-Analysis. Miao R

The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review.

40. J Transl Med. 2024 Mar 1;22(1):225. doi: 10.1186/s12967-024-05011-2. The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review. Nie Q(#)(1), Li M(#)(1), Huang C(2), Yuan Y(1), Liang Q(1), Ma X(2), Qiu T(1)(2), L

Impact of Berberine or Berberine Combination Products on Lipoprotein, Triglyceride and Biological Safety Marker Concentrations in Patients with Hyperlipidemia: A Systematic Review and Meta-Analysis.

47. J Diet Suppl. 2024;21(2):242-259. doi: 10.1080/19390211.2023.2212762. Epub 2023 May 14. Impact of Berberine or Berberine Combination Products on Lipoprotein, Triglyceride and Biological Safety Marker Concentrations in Patients with Hyperlipidemia: A Systematic Review and Meta-Analysis. Hern

Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials.

7. Phytomedicine. 2023 Apr;112:154716. doi: 10.1016/j.phymed.2023.154716. Epub 2023 Feb 12. Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials. Yang L(1), Zhu W(1), Zhang X(1), Zhou X(1), Wu W(2), Shen T(3).

The Effect of Berberine on Metabolic Profiles in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

11. Oxid Med Cell Longev. 2021 Dec 15;2021:2074610. doi: 10.1155/2021/2074610. eCollection 2021. The Effect of Berberine on Metabolic Profiles in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Guo J(1), Chen H(1)(2), Zhang X(1), Lou W(1), Zhang P

[Systematic review and Meta-analysis on efficacy and safety of berberine for dyslipidemia].

30. Zhongguo Zhong Yao Za Zhi. 2020 Feb;45(3):664-673. doi: 10.19540/j.cnki.cjcmm.20190626.501. [Systematic review and Meta-analysis on efficacy and safety of berberine for dyslipidemia]. [Article in Chinese] Zhao Y(1), Yang YY(1), DU YW(1), Yang HM(1), Wu SX(1). Author information: (1)Dongzhi

Berberine and Dyslipidemia: Different Applications and Biopharmaceutical Formulations Without Statin-Like Molecules-A Meta-Analysis.

5. J Med Food. 2020 Feb;23(2):101-113. doi: 10.1089/jmf.2019.0088. Epub 2019 Aug 23. Berberine and Dyslipidemia: Different Applications and Biopharmaceutical Formulations Without Statin-Like Molecules-A Meta-Analysis. Bertuccioli A(1), Moricoli S(1), Amatori S(2), Rocchi MBL(2), Vici G(3), Sisti

Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials.

22. Am J Chin Med. 2019;47(4):751-767. doi: 10.1142/S0192415X19500393. Epub 2019 May 16. Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials. Zhang LS(1), Zhang JH(1),

Metabolic effect of berberine-silymarin association: A meta-analysis of randomized, double-blind, placebo-controlled clinical trials.

26. Phytother Res. 2019 Apr;33(4):862-870. doi: 10.1002/ptr.6282. Epub 2019 Jan 10. Metabolic effect of berberine-silymarin association: A meta-analysis of randomized, double-blind, placebo-controlled clinical trials. Fogacci F(1), Grassi D(2)(3), Rizzo M(4)(3), Cicero AFG(1)(3). Author informat