카이엔 페퍼 (캡사이신)

The effect of red pepper/capsaicin on cardiovascular risk factors: a systematic review, meta-analysis, and GRADE assessment.

1. Nutr Metab Cardiovasc Dis. 2026 Jun;36(6):104616. doi: 10.1016/j.numecd.2026.104616. Epub 2026 Feb 14. The effect of red pepper/capsaicin on cardiovascular risk factors: a systematic review, meta-analysis, and GRADE assessment. Ghoreishy SM(1), Zeydi M(2), Hadi V(3), Jafarbeglou N(4), Atabaki

The effect of red pepper/capsaicin on blood pressure and heart rate: A systematic review and meta-analysis of clinical trials.

2. Phytother Res. 2021 Nov;35(11):6080-6088. doi: 10.1002/ptr.7217. Epub 2021 Oct 22. The effect of red pepper/capsaicin on blood pressure and heart rate: A systematic review and meta-analysis of clinical trials. Shirani F(1), Foshati S(2), Tavassoly M(3), Clark CCT(4), Rouhani MH(3). Author in

[Christmas article: Can chili improve the performance of Santa Claus and goblins? A randomized study].

3. Ugeskr Laeger. 2024 Dec 9;186(50):V202410. doi: 10.61409/V202410. [Christmas article: Can chili improve the performance of Santa Claus and goblins? A randomized study]. [Article in Danish] Rasmussen S(1), Rasmussen JK(2). Author information: (1)Klinisk Institut, Aalborg Universitet. (2)Datal

Ten weeks of Capsicum annuum L. extract supplementation did not change adipose tissue-derived hormones, appetite, body composition, and muscle strength when combined with resistance training in healthy untrained men: A clinical trial study.

4. Nutr Res. 2024 Feb;122:33-43. doi: 10.1016/j.nutres.2023.11.010. Epub 2023 Dec 5. Ten weeks of Capsicum annuum L. extract supplementation did not change adipose tissue-derived hormones, appetite, body composition, and muscle strength when combined with resistance training in healthy untrained

Qingke β-glucan synergizes with a β-glucan-utilizing Lactobacillus strain to relieve capsaicin-induced gastrointestinal injury in mice.

5. Int J Biol Macromol. 2021 Mar 31;174:289-299. doi: 10.1016/j.ijbiomac.2021.01.164. Epub 2021 Jan 29. Qingke β-glucan synergizes with a β-glucan-utilizing Lactobacillus strain to relieve capsaicin-induced gastrointestinal injury in mice. Tang T(1), Song J(2), Wang H(2), Zhang Y(2), Xin J(3), S

Sinergism between alkaloids piperine and capsaicin with meglumine antimoniate against Leishmania infantum.

6. Exp Parasitol. 2018 May;188:79-82. doi: 10.1016/j.exppara.2018.04.001. Epub 2018 Apr 3. Sinergism between alkaloids piperine and capsaicin with meglumine antimoniate against Leishmania infantum. Vieira-Araújo FM(1), Macedo Rondon FC(1), Pinto Vieira ÍG(2), Pereira Mendes FN(2), Carneiro de F

Capsaicin and Piperine Can Overcome Multidrug Resistance in Cancer Cells to Doxorubicin.

7. Molecules. 2018 Mar 2;23(3):557. doi: 10.3390/molecules23030557. Capsaicin and Piperine Can Overcome Multidrug Resistance in Cancer Cells to Doxorubicin. Li H(1), Krstin S(2), Wang S(3), Wink M(4). Author information: (1)Institute of Pharmacy and Molecular Biotechnology, Heidelberg University

Capsaicin enhances the antitumor activity of sorafenib in hepatocellular carcinoma cells and mouse xenograft tumors through increased ERK signaling.

8. Acta Pharmacol Sin. 2018 Mar;39(3):438-448. doi: 10.1038/aps.2017.156. Epub 2017 Nov 30. Capsaicin enhances the antitumor activity of sorafenib in hepatocellular carcinoma cells and mouse xenograft tumors through increased ERK signaling. Zhang SS(1), Ni YH(1), Zhao CR(1), Qiao Z(1), Yu HX(1),

Antimicrobial Activity of Selected Polyphenols and Capsaicinoids Identified in Pepper (Capsicum annuum L.) and Their Possible Mode of Interaction.

9. Curr Microbiol. 2017 Nov;74(11):1253-1260. doi: 10.1007/s00284-017-1310-2. Epub 2017 Jul 18. Antimicrobial Activity of Selected Polyphenols and Capsaicinoids Identified in Pepper (Capsicum annuum L.) and Their Possible Mode of Interaction. Mokhtar M(1), Ginestra G(2), Youcefi F(3), Filocamo A

Anticancer Properties of Capsaicin Against Human Cancer.

10. Anticancer Res. 2016 Mar;36(3):837-43. Anticancer Properties of Capsaicin Against Human Cancer. Clark R(1), Lee SH(2). Author information: (1)Department of Nutrition and Food Science, College of Agriculture and Natural Resources, University of Maryland, College Park, MD, U.S.A. (2)Department

The anti-inflammatory effect of diclofenac is considerably augmented by topical capsaicinoids-containing patch in carrageenan-induced paw oedema of rat.

11. Inflammopharmacology. 2013 Dec;21(6):413-9. doi: 10.1007/s10787-013-0175-7. Epub 2013 Jun 24. The anti-inflammatory effect of diclofenac is considerably augmented by topical capsaicinoids-containing patch in carrageenan-induced paw oedema of rat. Ercan N(1), Uludag MO, Agis ER, Demirel-Yilma

Food-drug interactions: effect of capsaicin on the pharmacokinetics of simvastatin and its active metabolite in rats.

12. Food Chem Toxicol. 2013 Mar;53:168-73. doi: 10.1016/j.fct.2012.11.045. Epub 2012 Dec 5. Food-drug interactions: effect of capsaicin on the pharmacokinetics of simvastatin and its active metabolite in rats. Zhai XJ(1), Chen JG, Liu JM, Shi F, Lu YN. Author information: (1)Department of Pharm

Dietary agonists of TRPV1 inhibit gastric acid secretion in mice.

13. Planta Med. 2012 Nov;78(17):1801-6. doi: 10.1055/s-0032-1315387. Epub 2012 Oct 9. Dietary agonists of TRPV1 inhibit gastric acid secretion in mice. Okumi H(1), Tashima K, Matsumoto K, Namiki T, Terasawa K, Horie S. Author information: (1)Laboratory of Pharmacology, Faculty of Pharmaceutical

Food-drug interactions: effect of capsaicin on the pharmacokinetics of galantamine in rats.

14. Xenobiotica. 2012 Nov;42(11):1151-5. doi: 10.3109/00498254.2012.693220. Epub 2012 Jun 5. Food-drug interactions: effect of capsaicin on the pharmacokinetics of galantamine in rats. Zhai XJ(1), Lu YN. Author information: (1)Department of Pharmacy, Union Hospital, Huazhong University of Scien

[Combination effects of capsicum plaster at the Korean hand acupuncture points k-d2 with prophylactic antiemetic on postoperative nausea and vomiting after gynecologic laparoscopy].

15. J Korean Acad Nurs. 2013 Apr;43(2):215-24. doi: 10.4040/jkan.2013.43.2.215. [Combination effects of capsicum plaster at the Korean hand acupuncture points k-d2 with prophylactic antiemetic on postoperative nausea and vomiting after gynecologic laparoscopy]. [Article in Korean] Jung HJ(1), P

The effect of capsaicin, capsinoids, and pepper-based interventions on lipid profiles in overweight or obese individuals: a systematic review and meta-analysis of randomized controlled trials.

10. Diabetes Res Clin Pract. 2025 Nov;229:112478. doi: 10.1016/j.diabres.2025.112478. Epub 2025 Sep 10. The effect of capsaicin, capsinoids, and pepper-based interventions on lipid profiles in overweight or obese individuals: a systematic review and meta-analysis of randomized controlled trials.

Genetic Influence on Capsaicin Tolerance: Precision Nutrition Implications for Obesity Handling.

45. Lifestyle Genom. 2024;17(1):57-63. doi: 10.1159/000539293. Epub 2024 May 29. Genetic Influence on Capsaicin Tolerance: Precision Nutrition Implications for Obesity Handling. Ramos-Lopez O(1), Martinez-Aceviz Y(1), Sobrevilla-Navarro AA(1)(2), Chavez-Mendez JR(3). Author information: (1)Medi

A Little Pepper-Upper? Systematic Review of Randomized Controlled Studies on Capsaicinoids, Capsinoids, and Exercise Performance.

34. Int J Sport Nutr Exerc Metab. 2023 Jul 6;33(5):291-301. doi: 10.1123/ijsnem.2023-0016. Print 2023 Sep 1. A Little Pepper-Upper? Systematic Review of Randomized Controlled Studies on Capsaicinoids, Capsinoids, and Exercise Performance. Sukan-Karaçağıl B(1), Akbulut G(1), Açar Y(1), Demirkopar

Spicy Food and Chili Peppers and Multiple Health Outcomes: Umbrella Review.

9. Mol Nutr Food Res. 2022 Dec;66(23):e2200167. doi: 10.1002/mnfr.202200167. Epub 2022 Oct 19. Spicy Food and Chili Peppers and Multiple Health Outcomes: Umbrella Review. Ao Z(1), Huang Z(1)(2), Liu H(1). Author information: (1)Department of Integrated Traditional and Western Medicine, West Chin

Capsaicin intake and oral carcinogenesis: A systematic review.

20. Med Oral Patol Oral Cir Bucal. 2021 Mar 1;26(2):e261-e268. doi: 10.4317/medoral.24570. Capsaicin intake and oral carcinogenesis: A systematic review. Mosqueda-Solís A(1), Lafuente-Ibáñez de Mendoza I, Aguirre-Urizar JM, Mosqueda-Taylor A. Author information: (1)Health Care Department Autono

Health impacts of chemical irritants used for crowd control: a systematic review of the injuries and deaths caused by tear gas and pepper spray.

19. BMC Public Health. 2017 Oct 19;17(1):831. doi: 10.1186/s12889-017-4814-6. Health impacts of chemical irritants used for crowd control: a systematic review of the injuries and deaths caused by tear gas and pepper spray. Haar RJ(1), Iacopino V(2), Ranadive N(3), Weiser SD(4), Dandu M(4). Autho

Could capsaicinoids help to support weight management? A systematic review and meta-analysis of energy intake data.

50. Appetite. 2014 Feb;73:183-8. doi: 10.1016/j.appet.2013.11.005. Epub 2013 Nov 15. Could capsaicinoids help to support weight management? A systematic review and meta-analysis of energy intake data. Whiting S(1), Derbyshire EJ(2), Tiwari B(3). Author information: (1)School of Healthcare Scienc

Topical herbal therapies for treating osteoarthritis.

31. Cochrane Database Syst Rev. 2013 May 31;2013(5):CD010538. doi: 10.1002/14651858.CD010538. Topical herbal therapies for treating osteoarthritis. Cameron M(1), Chrubasik S. Author information: (1)School ofHealth and Sport Sciences,University of the SunshineCoast,MaroochydoreDC, Australia. mca

Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence.

35. Appetite. 2012 Oct;59(2):341-8. doi: 10.1016/j.appet.2012.05.015. Epub 2012 May 22. Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence. Whiting S(1), Derbyshire E, Tiwari BK. Author information: (1)Manchester Food Research Centre, Manch