사상자

Osthole enhances TRAIL-mediated apoptosis through downregulation of c-FLIP expression in renal carcinoma Caki cells.

1. Oncol Rep. 2017 Apr;37(4):2348-2354. doi: 10.3892/or.2017.5490. Epub 2017 Mar 6. Osthole enhances TRAIL-mediated apoptosis through downregulation of c-FLIP expression in renal carcinoma Caki cells. Min KJ(1), Han MA(1), Kim S(1), Park JW(1), Kwon TK(1). Author information: (1)Department of Im

Bioavailability enhancement of osthole after oral administration of Bushen Yizhi prescription extract to rats followed by Cnidium monnieri (L.) Cusson fruits extract in comparison to pure osthole at different doses.

2. J Ethnopharmacol. 2014 Mar 14;152(2):266-71. doi: 10.1016/j.jep.2013.09.045. Epub 2013 Oct 16. Bioavailability enhancement of osthole after oral administration of Bushen Yizhi prescription extract to rats followed by Cnidium monnieri (L.) Cusson fruits extract in comparison to pure osthole at

Neuroprotective effect of osthole against oxygen and glucose deprivation in rat cortical neurons: involvement of mitogen-activated protein kinase pathway.

3. Neuroscience. 2011 Jun 2;183:203-11. doi: 10.1016/j.neuroscience.2011.03.038. Epub 2011 Mar 29. Neuroprotective effect of osthole against oxygen and glucose deprivation in rat cortical neurons: involvement of mitogen-activated protein kinase pathway. Chen T(1), Liu W, Chao X, Qu Y, Zhang L, L

Topical Chinese herbal medicine in treating atopic dermatitis (eczema): A systematic review and meta-analysis with core herbs exploration.

4. J Ethnopharmacol. 2023 Dec 5;317:116790. doi: 10.1016/j.jep.2023.116790. Epub 2023 Jun 14. Topical Chinese herbal medicine in treating atopic dermatitis (eczema): A systematic review and meta-analysis with core herbs exploration. Wang MC(1), Chou YT(2), Kao MC(3), Lin QY(4), Chang SY(5), Chen

Topical herbal medicine combined with pharmacotherapy for psoriasis: a systematic review and meta-analysis.

1. Arch Dermatol Res. 2013 Apr;305(3):179-89. doi: 10.1007/s00403-013-1316-y. Epub 2013 Jan 26. Topical herbal medicine combined with pharmacotherapy for psoriasis: a systematic review and meta-analysis. Deng S(1), May BH, Zhang AL, Lu C, Xue CC. Author information: (1)School of Health Sciences, College of Science Engineering and Health, Traditional and Complementary Medicine Research Program, RMIT Health Innovations Research Institute (HIRi), RMIT University, PO Box 71, Bundoora, VIC, 3083, Australia. This systematic review examines the current state of the evidence for the efficacy and safety of herbal medicines (HMs) used topically in conjunction with anti-psoriatic pharmacotherapy (APP) in the treatment of psoriasis. Searches were conducted in September 2012 of PubMed, EMBASE, Cochrane Library, two Chinese databases (China National Knowledge Infrastructure and Chinese Scientific Journals Full Text Database) and of article reference lists. We included randomized controlled trials published in English, Chinese or Japanese that investigated topical HM combined with APP used systemically and/or topically compared to pharmacotherapy alone. Studies employing phototherapy were excluded. Two authors conducted searches, extracted data on study characteristics and outcomes, and assessed Risk of Bias. Disagreements were resolved by discussion with a third author. Eight studies met the inclusion criteria. All used multi-herb formulae, four in herbal baths, three in herbal ointments or creams, and one as herbal steam. The pooled data indicated a benefit for the add-on effect of herbal therapy to APP. Adding these topical HMs to conventional pharmacotherapy appeared to produce short-term additional clinical benefits. No serious adverse events were reported. Experimental studies suggest that some of the herbs possess anti-inflammatory, anti-pruritic, and/or anti-proliferative activities. However, these results need to be interpreted with caution due to methodological weaknesses and the lack of replicated studies. Studies that address the identified methodological deficiencies are required to further investigate the efficacy and safety of these HMs as adjunct therapies for psoriasis. DOI: 10.1007/s00403-013-1316-y PMID: 23354931 [Indexed for MEDLINE]

Efficacy of the kampo medicine xiong-gui-tiao-xue-yin (kyuki-chouketsu-in), a traditional herbal medicine, in the treatment of maternity blues syndrome in the postpartum period.

2. Am J Chin Med. 2005;33(1):117-26. doi: 10.1142/S0192415X05002710. Efficacy of the kampo medicine xiong-gui-tiao-xue-yin (kyuki-chouketsu-in), a traditional herbal medicine, in the treatment of maternity blues syndrome in the postpartum period. Ushiroyama T(1), Sakuma K, Ueki M. Author information: (1)Department of Obstetrics and Gynecology, Osaka Medical College Takatsuki, Osaka 568-8686, Japan. gyn003@poh.osaka-med.ac.jp This study was to evaluate the clinical efficacy of Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in), a Japanese traditional herbal medicine, in stabilizing postpartum psychological state. We enrolled 268 women who had a normal delivery in Osaka Medical College Hospital or its affiliated clinics and randomly assigned them to the following two groups: a group of 134 women who received Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) at a dose of 6.0 g/day and another group of 134 women without Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) (control group). We observed 2.06-fold and 1.67-fold higher incidences of depressive mood and nervousness, respectively, after delivery in the control group than in the Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) group. Within 3 weeks of postpartum, there was a significant difference in the incidences of maternity blues between the Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) group (15.7%; 21/134) and the control group (32.1%; 43/134) (p = 0.0195). No adverse effects were observed in this study. The results of this study demonstrate the beneficial clinical effects of Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) in stabilizing psychological state in the postpartum period. Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) can be expected to improve the mental health of women in the postpartum period and prevent maternity blues. DOI: 10.1142/S0192415X05002710 PMID: 15844839 [Indexed for MEDLINE]