동충하초

The Effectiveness of Yong Chong Cao Capsule in Patients With Mild to Severe COPD: A Multi-Center, Randomized, Active-Controlled Trial.

1. J Evid Based Med. 2025 Dec;18(4):e70091. doi: 10.1111/jebm.70091. Epub 2025 Nov 26. The Effectiveness of Yong Chong Cao Capsule in Patients With Mild to Severe COPD: A Multi-Center, Randomized, Active-Controlled Trial. Li S(1)(2)(3), Xie Y(1)(2)(3), Lin L(4), Wu L(5), Yu X(6), Ma Z(7), Yin Q(

Effect of a New Skin-Lightening Cosmetic Containing Cordyceps Extract in the Treatment of Melasma: A Clinical Trial.

2. J Cosmet Dermatol. 2025 Jul;24(7):e70329. doi: 10.1111/jocd.70329. Effect of a New Skin-Lightening Cosmetic Containing Cordyceps Extract in the Treatment of Melasma: A Clinical Trial. Shen S(1), Yao H(2), Zhu Y(3), Xiang W(3). Author information: (1)Department of Medical Cosmetology, Zhejiang

Effect of the Administration of Cordyceps militaris Mycelium Extract on Blood Markers for Anemia in Long-Distance Runners.

3. Nutrients. 2024 Jun 11;16(12):1835. doi: 10.3390/nu16121835. Effect of the Administration of Cordyceps militaris Mycelium Extract on Blood Markers for Anemia in Long-Distance Runners. Nakamura A(1), Shinozaki E(2)(3), Suzuki Y(3), Santa K(4)(5), Kumazawa Y(6)(7), Kobayashi F(8), Nagaoka I(5)(

A randomized controlled clinical trial examining the effects of Cordyceps militaris beverage on the immune response in healthy adults.

4. Sci Rep. 2024 Apr 5;14(1):7994. doi: 10.1038/s41598-024-58742-z. A randomized controlled clinical trial examining the effects of Cordyceps militaris beverage on the immune response in healthy adults. Ontawong A(1), Pengnet S(1), Thim-Uam A(2), Munkong N(3), Narkprasom N(4), Narkprasom K(4), K

Cordyceps sinensis accelerates stem cell recruitment to human skeletal muscle after exercise.

5. Food Funct. 2024 Apr 22;15(8):4010-4020. doi: 10.1039/d3fo03770c. Cordyceps sinensis accelerates stem cell recruitment to human skeletal muscle after exercise. Dewi L(1)(2), Liao YC(1), Jean WH(3), Huang KC(4), Huang CY(5)(6)(7)(8), Chen LK(9)(10)(11), Nicholls A(1), Lai LF(1), Kuo CH(1)(12)(

Efficacy of Cordyceps cicadae (Ascomycota) Mycelium Supplementation for Amelioration of Dry Eye Symptoms: A Randomized, Double-Blind Clinical Pilot Study.

6. Int J Med Mushrooms. 2022;24(12):57-67. doi: 10.1615/IntJMedMushrooms.2022045307. Efficacy of Cordyceps cicadae (Ascomycota) Mycelium Supplementation for Amelioration of Dry Eye Symptoms: A Randomized, Double-Blind Clinical Pilot Study. Chang HH(1), Chang WJ(2), Jhou BY(3), Kuo SY(4), Hsu JH

Synergistic Effect of HAD-B1 and Osimertinib Against Gefitinib Resistant HCC827 Non-Small Cell Lung Cancer Cells.

7. Integr Cancer Ther. 2025 Jan-Dec;24:15347354241307006. doi: 10.1177/15347354241307006. Synergistic Effect of HAD-B1 and Osimertinib Against Gefitinib Resistant HCC827 Non-Small Cell Lung Cancer Cells. Ko EJ(1), Kwag EB(2), Park JH(3), Cho SH(4), Park SJ(5), Jung MK(6), Kang IC(4)(7), Yoo HS(

Cordycepin enhances the Anticancer efficacy of PD-L1 blockade by modulating the tumor microenvironment of colon cancer.

8. Eur J Pharmacol. 2024 Dec 15;985:177089. doi: 10.1016/j.ejphar.2024.177089. Epub 2024 Nov 1. Cordycepin enhances the Anticancer efficacy of PD-L1 blockade by modulating the tumor microenvironment of colon cancer. Feng C(1), Chen R(2), Gao X(3), Fang W(4), Wu S(5), Chen L(6), Zheng X(7), Ji X

The synergistic effect of Cordyceps sinensis and Gymnema inodorum (Lour.) Decne. extracts on amelioration of glucose intolerance and dyslipidemia in high-fat diet-fed mice.

9. Nat Prod Res. 2025 Sep;39(18):5313-5317. doi: 10.1080/14786419.2024.2369235. Epub 2024 Jun 17. The synergistic effect of Cordyceps sinensis and Gymnema inodorum (Lour.) Decne. extracts on amelioration of glucose intolerance and dyslipidemia in high-fat diet-fed mice. Sirichaiwetchakoon K(1),

Virtual Screening for Biomimetic Anti-Cancer Peptides from Cordyceps militaris Putative Pepsinized Peptidome and Validation on Colon Cancer Cell Line.

10. Molecules. 2021 Sep 23;26(19):5767. doi: 10.3390/molecules26195767. Virtual Screening for Biomimetic Anti-Cancer Peptides from Cordyceps militaris Putative Pepsinized Peptidome and Validation on Colon Cancer Cell Line. Chantawannakul J(1), Chatpattanasiri P(1), Wattayagorn V(2), Kongsema M(2)

Cordycepin Augments the Chemosensitivity of Human Glioma Cells to Temozolomide by Activating AMPK and Inhibiting the AKT Signaling Pathway.

11. Mol Pharm. 2018 Nov 5;15(11):4912-4925. doi: 10.1021/acs.molpharmaceut.8b00551. Epub 2018 Oct 17. Cordycepin Augments the Chemosensitivity of Human Glioma Cells to Temozolomide by Activating AMPK and Inhibiting the AKT Signaling Pathway. Bi Y(1), Li H(2), Yi D(1), Sun Y(1), Bai Y(1), Zhong S

Synergistic antitumor efficacy of antibacterial helvolic acid from Cordyceps taii and cyclophosphamide in a tumor mouse model.

12. Exp Biol Med (Maywood). 2017 Jan;242(2):214-222. doi: 10.1177/1535370216668051. Epub 2016 Oct 4. Synergistic antitumor efficacy of antibacterial helvolic acid from Cordyceps taii and cyclophosphamide in a tumor mouse model. Xiao JH(1), Zhang Y(1), Liang GY(1), Liu RM(1), Li XG(1), Zhang LT(1

Cordycepin-enriched WIB801C from Cordyceps militaris inhibits ADP-induced [Ca(2+)] i mobilization and fibrinogen binding via phosphorylation of IP 3R and VASP.

13. Arch Pharm Res. 2015 Jan;38(1):81-97. doi: 10.1007/s12272-014-0436-z. Epub 2014 Jul 9. Cordycepin-enriched WIB801C from Cordyceps militaris inhibits ADP-induced [Ca(2+)] i mobilization and fibrinogen binding via phosphorylation of IP 3R and VASP. Lee DH(1), Kwon HW, Kim HH, Lim DH, Nam GS,

Oral Chinese herbal medicine combined with pharmacotherapy for stable COPD: a systematic review of effect on BODE index and six minute walk test.

14. PLoS One. 2014 Mar 12;9(3):e91830. doi: 10.1371/journal.pone.0091830. eCollection 2014. Oral Chinese herbal medicine combined with pharmacotherapy for stable COPD: a systematic review of effect on BODE index and six minute walk test. Chen X(1), May B(2), Di YM(2), Zhang AL(2), Lu C(3), Xue C

[Investigation of compound, compatibility of Rhodiola crenulata, Cordyceps militaris, and Rhum palmatum, on metabolic syndrome treatment VI--improving hyperglycemia-mediated renal damage].

15. Zhongguo Zhong Yao Za Zhi. 2013 Nov;38(22):3961-6. [Investigation of compound, compatibility of Rhodiola crenulata, Cordyceps militaris, and Rhum palmatum, on metabolic syndrome treatment VI--improving hyperglycemia-mediated renal damage]. [Article in Chinese] Fu JY(1), Zhang XL(2), Tian JY

Cordyceps sinensis polysaccharide CPS-2 protects human mesangial cells from PDGF-BB-induced proliferation through the PDGF/ERK and TGF-β1/Smad pathways.

16. Mol Cell Endocrinol. 2014 Feb 15;382(2):979-88. doi: 10.1016/j.mce.2013.11.018. Epub 2013 Dec 2. Cordyceps sinensis polysaccharide CPS-2 protects human mesangial cells from PDGF-BB-induced proliferation through the PDGF/ERK and TGF-β1/Smad pathways. Wang Y(1), Liu D(2), Zhao H(2), Jiang H(3)

Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials.

37. Appl Microbiol Biotechnol. 2020 Jun;104(11):4675-4703. doi: 10.1007/s00253-020-10476-4. Epub 2020 Apr 9. Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials. Wong JH(1), Ng TB

Multi-center, randomized, double-blind, placebo-controlled, exploratory study to evaluate the efficacy and safety of HAD-B1 for dose-finding in EGFR positive and locally advanced or metastatic NSCLC subjects who need Afatinib therapy: Study protocol clinical trial (SPIRIT Compliant).

22. Medicine (Baltimore). 2020 Jan;99(4):e18735. doi: 10.1097/MD.0000000000018735. Multi-center, randomized, double-blind, placebo-controlled, exploratory study to evaluate the efficacy and safety of HAD-B1 for dose-finding in EGFR positive and locally advanced or metastatic NSCLC subjects who ne

Cordyceps militaris Enhances Cell-Mediated Immunity in Healthy Korean Men.

22. J Med Food. 2015 Oct;18(10):1164-72. doi: 10.1089/jmf.2014.3350. Epub 2015 Aug 18. Cordyceps militaris Enhances Cell-Mediated Immunity in Healthy Korean Men. Kang HJ(1), Baik HW(1), Kim SJ(1), Lee SG(2), Ahn HY(3), Park JS(1), Park SJ(1), Jang EJ(1), Park SW(1), Choi JY(1), Sung JH(1), Lee S

A toxicological study of HangAmDan-B in mice.

3. J Acupunct Meridian Stud. 2011 Mar;4(1):54-60. doi: 10.1016/S2005-2901(11)60007-1. A toxicological study of HangAmDan-B in mice. Yoo HS(1), Lee HJ, Kim JS, Yoon J, Lee GH, Lee YW, Cho CK. Author information: (1)East-West Cancer Center, College of Oriental Medicine, Daejeon University, Daejeo

[Treatment of hyperlipidemia with cultivated Cordyceps--a double-blind, randomized placebo control trial].

40. Zhong Xi Yi Jie He Za Zhi. 1985 Nov;5(11):652-4, 642. [Treatment of hyperlipidemia with cultivated Cordyceps--a double-blind, randomized placebo control trial]. [Article in Chinese] Shao G. PMID: 2938807 [Indexed for MEDLINE]

Fungi-Based Bioproducts: A Review in the Context of One Health.

43. Pathogens. 2025 May 9;14(5):463. doi: 10.3390/pathogens14050463. Fungi-Based Bioproducts: A Review in the Context of One Health. de Sousa TK(1), Silva ATD(2), Soares FEF(1)(2). Author information: (1)Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Rua 235 s/n,

Edible and Medicinal Fungi as Candidate Natural Antidepressants: Mechanisms and Nutritional Implications.

1. Mol Nutr Food Res. 2025 Jun;69(12):e70080. doi: 10.1002/mnfr.70080. Epub 2025 Apr 27. Edible and Medicinal Fungi as Candidate Natural Antidepressants: Mechanisms and Nutritional Implications. Gong P(1)(2)(3), Wang J(1)(2)(3), Long H(1)(2)(3), Yang W(1)(2)(3), Chen X(1)(2)(3), Li N(1)(2)(3),

A systematic review on polysaccharides from fermented Cordyceps sinensis: Advances in the preparation, structural characterization, bioactivities, structure-activity relationships.

5. Int J Biol Macromol. 2024 Dec;282(Pt 5):137275. doi: 10.1016/j.ijbiomac.2024.137275. Epub 2024 Nov 5. A systematic review on polysaccharides from fermented Cordyceps sinensis: Advances in the preparation, structural characterization, bioactivities, structure-activity relationships. Yao L(1),

Adjuvant treatment with Cordyceps sinensis for lung cancer: A systematic review and meta-analysis of randomized controlled trials.

44. J Ethnopharmacol. 2024 Jun 12;327:118044. doi: 10.1016/j.jep.2024.118044. Epub 2024 Mar 12. Adjuvant treatment with Cordyceps sinensis for lung cancer: A systematic review and meta-analysis of randomized controlled trials. Wang C(1), Wang J(1), Qi Y(2). Author information: (1)Shandong Unive

Fermented Ophiocordyceps sinensis mycelium products for preventing contrast-associated acute kidney injury: a systematic review of randomized controlled trials.

23. Ren Fail. 2024 Dec;46(1):2300302. doi: 10.1080/0886022X.2023.2300302. Epub 2024 Jan 8. Fermented Ophiocordyceps sinensis mycelium products for preventing contrast-associated acute kidney injury: a systematic review of randomized controlled trials. Pu F(1), Li T(2), Shen C(1), Wang Y(3), Tan

Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies.

42. Curr Oncol Rep. 2023 Jun;25(6):569-587. doi: 10.1007/s11912-023-01408-2. Epub 2023 Mar 30. Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies. Narayanan S(1), de Mores AR(2), Cohen L(2), Anwar MM(3), Lazar F(4), Hicklen R(5), Lopez G(2), Yang P(2), Bruera E(2)

The effects of Ophiocordyceps sinensis combined with ACEI/ARB on diabetic kidney disease: A systematic review and meta-analysis.

19. Phytomedicine. 2023 Jan;108:154531. doi: 10.1016/j.phymed.2022.154531. Epub 2022 Oct 30. The effects of Ophiocordyceps sinensis combined with ACEI/ARB on diabetic kidney disease: A systematic review and meta-analysis. Yan G(1), Chang T(2), Zhao Y(2), Yu M(2), Mi J(2), Wang G(2), Wang X(3), L

Efficacy and safety of Corbrin Capsule on malnutrition, inflammation, and atherosclerosis syndrome in patients with uremia: systematic review and meta-analysis.

25. Ann Palliat Med. 2022 Apr;11(4):1431-1440. doi: 10.21037/apm-22-291. Efficacy and safety of Corbrin Capsule on malnutrition, inflammation, and atherosclerosis syndrome in patients with uremia: systematic review and meta-analysis. Rui Z(1), Wang Y(1), Wang N(1), Wang J(1). Author information

Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis.

33. J Tradit Chin Med. 2019 Feb;39(1):1-14. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. Bee Yean O(1), Zoriah A(2). Author information: (1)Zoriah Aziz, Department of Pharmacy, Faculty of Medicine, University of Malay