히알루론산 (관절)

Stem cell injections for osteoarthritis of the knee.

1. Cochrane Database Syst Rev. 2025 Apr 2;4(4):CD013342. doi: 10.1002/14651858.CD013342.pub2. Stem cell injections for osteoarthritis of the knee. Whittle SL(1)(2), Johnston RV(1), McDonald S(3), Worthley D(4), Campbell TM(5), Cyril S(1), Bapna T(1), Zhang J(1), Buchbinder R(1). Author informat

Efficacy and safety of arthroscopic surgery combined with hyaluronic acid for meniscal injuries: A systematic review and meta-analysis of randomized controlled studies.

2. J Orthop Surg (Hong Kong). 2023 Jan-Apr;31(1):10225536231156699. doi: 10.1177/10225536231156699. Efficacy and safety of arthroscopic surgery combined with hyaluronic acid for meniscal injuries: A systematic review and meta-analysis of randomized controlled studies. Dong Z(1), Huang L(1), Wu

Efficacy and safety of mesenchymal stem cell injections for patients with osteoarthritis: a meta-analysis and review of RCTs.

3. Arch Orthop Trauma Surg. 2021 Jul;141(7):1241-1251. doi: 10.1007/s00402-020-03703-0. Epub 2021 Jan 28. Efficacy and safety of mesenchymal stem cell injections for patients with osteoarthritis: a meta-analysis and review of RCTs. Jiang P(#)(1), Mao L(#)(1), Qiao L(2), Lei X(1), Zheng Q(3), Li

[NON-ARTHROPLASTY TREATMENT FOR KNEE OSTEOARTHRITIS].

4. Harefuah. 2017 Jul;156(7):455-459. [NON-ARTHROPLASTY TREATMENT FOR KNEE OSTEOARTHRITIS]. [Article in Hebrew] Stahl I(1), Ginesin E(1), Hous N(1), Kotlyarsky P(1), Norman D(1), Peskin B(1). Author information: (1)Orthopedic Surgery Division - Rambam Health Care Campus. Osteoarthritis is chara

Cytopeutics umbilical cord-derived mesenchymal stem cells are associated with earlier clinical improvement compared to bone marrow aspirate concentrate with scaffold in knee cartilage injury: A Phase 1 feasibility and Phase 2 randomized controlled trial.

5. Med J Malaysia. 2026 Mar;81(2):234-245. Cytopeutics umbilical cord-derived mesenchymal stem cells are associated with earlier clinical improvement compared to bone marrow aspirate concentrate with scaffold in knee cartilage injury: A Phase 1 feasibility and Phase 2 randomized controlled trial

Circulating Metabolites Treat Human TMJ-OA by Eliminating Senescent Chondrocytes via the C1QBP/C1q/p14ARF Axis.

6. J Extracell Vesicles. 2026 Feb;15(2):e70224. doi: 10.1002/jev2.70224. Circulating Metabolites Treat Human TMJ-OA by Eliminating Senescent Chondrocytes via the C1QBP/C1q/p14ARF Axis. Meng B(#)(1), Li X(#)(2)(3), Yang B(#)(1), Qu Y(#)(1), He Y(1), Fu C(1), An Z(1), Wu A(2)(3), Hei Y(2)(3), Zhan

Platelet-rich plasma versus hyaluronic acid injection following arthrocentesis for temporomandibular joint disorders under sedation: a comparative clinical study.

7. Oral Maxillofac Surg. 2026 Jan 10;30(1):15. doi: 10.1007/s10006-025-01502-8. Platelet-rich plasma versus hyaluronic acid injection following arthrocentesis for temporomandibular joint disorders under sedation: a comparative clinical study. Mahdi MS(1), Abdulsattar MS(2). Author information:

Efficacy and safety of a single intra-articular injection of mannitol-combined hyaluronan in patients with knee osteoarthritis - A double-blinded randomized clinical study.

8. Knee. 2026 Jan;58:104292. doi: 10.1016/j.knee.2025.11.018. Epub 2025 Dec 11. Efficacy and safety of a single intra-articular injection of mannitol-combined hyaluronan in patients with knee osteoarthritis - A double-blinded randomized clinical study. Chen CY(1), Lu CC(2), Liou IH(1), Huang MH(

Efficacy of single intra-articular 2% sodium hyaluronate versus corticosteroid injection in isolated patellofemoral osteoarthritis: A double-blind, randomized controlled trial.

9. J ISAKOS. 2026 Feb;16:101038. doi: 10.1016/j.jisako.2025.101038. Epub 2025 Nov 15. Efficacy of single intra-articular 2% sodium hyaluronate versus corticosteroid injection in isolated patellofemoral osteoarthritis: A double-blind, randomized controlled trial. Mekariya K(1), Manop P(2), Chern

Cartilage Regeneration Potential in Early Osteoarthritis of the Knee: A Prospective, Randomized, Open, and Blinded Endpoint Study Comparing Adipose-Derived Mesenchymal Stem Cell (ADSC) Therapy Versus Hyaluronic Acid.

10. Int J Mol Sci. 2025 Aug 31;26(17):8476. doi: 10.3390/ijms26178476. Cartilage Regeneration Potential in Early Osteoarthritis of the Knee: A Prospective, Randomized, Open, and Blinded Endpoint Study Comparing Adipose-Derived Mesenchymal Stem Cell (ADSC) Therapy Versus Hyaluronic Acid. Tangkanj

Tuina improves patellofemoral osteoarthritis by alleviating the degree of lateral patellar tilt: a correlation analysis based on a randomized controlled trial.

11. Complement Ther Med. 2025 Oct;93:103234. doi: 10.1016/j.ctim.2025.103234. Epub 2025 Aug 24. Tuina improves patellofemoral osteoarthritis by alleviating the degree of lateral patellar tilt: a correlation analysis based on a randomized controlled trial. Gu J(1), Dong Y(1), Wei G(1), Zhuo Z(2)

Does ultrasound guidance during arthrocentesis in women with disc displacement without reduction reduce procedure time and improve outcomes? A randomized clinical trial.

12. Oral Maxillofac Surg. 2025 Aug 16;29(1):144. doi: 10.1007/s10006-025-01442-3. Does ultrasound guidance during arthrocentesis in women with disc displacement without reduction reduce procedure time and improve outcomes? A randomized clinical trial. Bahaa M(1), Azab AMFA(2), El Sheikh HMMA(3),

Does the Hyaluronic Acid Dosage During Arthrocentesis Influence Pain Reduction and Maximal Incisal Opening?

13. J Oral Maxillofac Surg. 2025 Nov;83(11):1344-1350. doi: 10.1016/j.joms.2025.06.227. Epub 2025 Jun 24. Does the Hyaluronic Acid Dosage During Arthrocentesis Influence Pain Reduction and Maximal Incisal Opening? Sahar O(1), Topal O(2). Author information: (1)Doctor of Dental Medicine, Departm

Evaluation of computer-guided visco-supplementation in the management of internal derangement of temporomandibular joint: a randomized controlled clinical trial.

14. Oral Surg Oral Med Oral Pathol Oral Radiol. 2025 Oct;140(4):416-427. doi: 10.1016/j.oooo.2025.04.098. Epub 2025 Apr 29. Evaluation of computer-guided visco-supplementation in the management of internal derangement of temporomandibular joint: a randomized controlled clinical trial. Atmeh BSK

Intra-articular injection of modified citrus pectin and hyaluronate gel induces synergistic effects in treating osteoarthritis.

15. Int J Biol Macromol. 2024 Sep;276(Pt 1):133840. doi: 10.1016/j.ijbiomac.2024.133840. Epub 2024 Jul 14. Intra-articular injection of modified citrus pectin and hyaluronate gel induces synergistic effects in treating osteoarthritis. Chen Y(1), Su D(1), Zheng J(1), He J(1), Du B(1), Duan R(1),

Combination Therapy of Metastatic Castration-Recurrent Prostate Cancer: Hyaluronic Acid Decorated, Cabazitaxel-Prodrug and Orlistat Co-Loaded Nano-System.

10. Drug Des Devel Ther. 2021 Aug 20;15:3605-3616. doi: 10.2147/DDDT.S306684. eCollection 2021. Combination Therapy of Metastatic Castration-Recurrent Prostate Cancer: Hyaluronic Acid Decorated, Cabazitaxel-Prodrug and Orlistat Co-Loaded Nano-System. Qu Z(1), Ren Y(1), Shen H(1), Wang H(1), Shi

Injectable anti-inflammatory hyaluronic acid hydrogel for osteoarthritic cartilage repair.

40. Mater Sci Eng C Mater Biol Appl. 2020 Oct;115:111096. doi: 10.1016/j.msec.2020.111096. Epub 2020 May 15. Injectable anti-inflammatory hyaluronic acid hydrogel for osteoarthritic cartilage repair. Jin Y(1), Koh RH(1), Kim SH(2), Kim KM(3), Park GK(4), Hwang NS(5). Author information: (1)Scho

Shea Nut Oil Extracts Enhance the Intra-Articular Sodium Hyaluronate Effectiveness on Surgically Induced OA Progression in Rats.

2. Nutrients. 2020 Mar 30;12(4):957. doi: 10.3390/nu12040957. Shea Nut Oil Extracts Enhance the Intra-Articular Sodium Hyaluronate Effectiveness on Surgically Induced OA Progression in Rats. Chen IJ(1)(2), Wong CS(1)(3). Author information: (1)Department of Anesthesiology, Cathay General Hospita

LL-37 alone and in combination with IL17A enhances proinflammatory cytokine expression in parallel with hyaluronan metabolism in human synovial sarcoma cell line SW982-A step toward understanding the development of inflammatory arthritis.

29. PLoS One. 2019 Jul 1;14(7):e0218736. doi: 10.1371/journal.pone.0218736. eCollection 2019. LL-37 alone and in combination with IL17A enhances proinflammatory cytokine expression in parallel with hyaluronan metabolism in human synovial sarcoma cell line SW982-A step toward understanding the de

Pharmacokinetics and four-week repeated-dose toxicity of hyaluronic acid and ketorolac combination following intra-articular administration in normal rats.

28. Regul Toxicol Pharmacol. 2019 Mar;102:79-89. doi: 10.1016/j.yrtph.2019.01.011. Epub 2019 Jan 3. Pharmacokinetics and four-week repeated-dose toxicity of hyaluronic acid and ketorolac combination following intra-articular administration in normal rats. Kim SH(1), Park KW(1), Kim JM(1), Ho MJ(

Intra-Articular Injection of Cross-Linked Hyaluronic Acid-Dexamethasone Hydrogel Attenuates Osteoarthritis: An Experimental Study in a Rat Model of Osteoarthritis.

5. Int J Mol Sci. 2016 Apr 15;17(4):411. doi: 10.3390/ijms17040411. Intra-Articular Injection of Cross-Linked Hyaluronic Acid-Dexamethasone Hydrogel Attenuates Osteoarthritis: An Experimental Study in a Rat Model of Osteoarthritis. Zhang Z(1), Wei X(2), Gao J(3), Zhao Y(4), Zhao Y(5), Guo L(6),

Two fluoroquinolones and their combinations with hyaluronan: comparison of effects on canine chondrocyte culture.

48. J Vet Pharmacol Ther. 2016 Oct;39(5):439-51. doi: 10.1111/jvp.12305. Epub 2016 Mar 11. Two fluoroquinolones and their combinations with hyaluronan: comparison of effects on canine chondrocyte culture. Siengdee P(1), Euppayo T(1), Buddhachat K(1), Chomdej S(2), Nganvongpanit K(1)(3). Author

Synergistic Effects of a Mixture of Glycosaminoglycans to Inhibit Adipogenesis and Enhance Chondrocyte Features in Multipotent Cells.

8. Cell Physiol Biochem. 2015;37(5):1792-806. doi: 10.1159/000438542. Epub 2015 Nov 13. Synergistic Effects of a Mixture of Glycosaminoglycans to Inhibit Adipogenesis and Enhance Chondrocyte Features in Multipotent Cells. Petrov PD, Granados N, Chetrit C, Martínez-Puig D, Palou A, Bonet ML. BAC

Direct chemotherapeutic dual drug delivery through intra-articular injection for synergistic enhancement of rheumatoid arthritis treatment.

42. Sci Rep. 2015 Oct 1;5:14713. doi: 10.1038/srep14713. Direct chemotherapeutic dual drug delivery through intra-articular injection for synergistic enhancement of rheumatoid arthritis treatment. Reum Son A(1), Kim DY(1), Hun Park S(1), Yong Jang J(1), Kim K(1), Ju Kim B(1), Yun Yin X(2), Ho Ki

A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis.

44. Nutrients. 2023 Aug 29;15(17):3769. doi: 10.3390/nu15173769. A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis. Hill

Intra-Articular Injections in Patients with Femoroacetabular Impingement: a Prospective, Randomized, Double-blind, Cross-over Study.

30. J Korean Med Sci. 2016 Nov;31(11):1822-1827. doi: 10.3346/jkms.2016.31.11.1822. Intra-Articular Injections in Patients with Femoroacetabular Impingement: a Prospective, Randomized, Double-blind, Cross-over Study. Lee YK(1), Lee GY(2)(3), Lee JW(2), Lee E(2), Kang HS(2). Author information: (

Treatment of painful osteoarthritis of the knee with hyaluronic acid. Results of a multicenter Asian study.

22. J Med Assoc Thai. 2001 Oct;84 Suppl 2:S576-81. Treatment of painful osteoarthritis of the knee with hyaluronic acid. Results of a multicenter Asian study. Bunyaratavej N(1), Chan KM, Subramanian N. Author information: (1)Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital

The Clinical Efficacy of Traditional Chinese Medicine Topical Therapy Combined with Sodium Hyaluronate Intra-articular Injection in the Treatment of Patellar Chondromalacia: a systematic review and meta-analysis.

30. Acta Orthop Belg. 2025 Dec;91(4):439-446. doi: 10.52628/91.4.13257. The Clinical Efficacy of Traditional Chinese Medicine Topical Therapy Combined with Sodium Hyaluronate Intra-articular Injection in the Treatment of Patellar Chondromalacia: a systematic review and meta-analysis. Bian H, Gu

Ceiling effects, mechanistic mismatch, and the need for standardized reporting in autologous concentrates for temporomandibular joint disorders.

7. Oral Maxillofac Surg. 2026 Feb 9;30(1):24. doi: 10.1007/s10006-026-01518-8. Ceiling effects, mechanistic mismatch, and the need for standardized reporting in autologous concentrates for temporomandibular joint disorders. Mourão CF(1), Juliasse LE(2)(3), Dos Santos Pereira R(2)(3). Author info

Effect of intraarticular drug injection in patients with temporomandibular joint disorders with limited mouth opening: a system review and network meta-analysis.

22. J Oral Facial Pain Headache. 2025 Dec;39(4):85-99. doi: 10.22514/jofph.2025.041. Epub 2025 Dec 12. Effect of intraarticular drug injection in patients with temporomandibular joint disorders with limited mouth opening: a system review and network meta-analysis. Zou S(1), Yue Y(2), Wang X(1),