I3C

Synergistic efficacy of polymyxin B and indole-3-carbinol against Klebsiella pneumoniae bloodstream infection.

1. Microb Pathog. 2025 Nov;208:108007. doi: 10.1016/j.micpath.2025.108007. Epub 2025 Aug 25. Synergistic efficacy of polymyxin B and indole-3-carbinol against Klebsiella pneumoniae bloodstream infection. Yang N(1), Chen H(1), Yang K(1), Liu L(1), Zhu Y(1), Lu J(1), Li X(1), Zhu R(1), Yang Y(1),

Synergistic action of indole-3-carbinol with membrane-active agents against multidrug-resistant Gram-negative bacteria.

2. Lett Appl Microbiol. 2023 Aug 2;76(8):ovad093. doi: 10.1093/lambio/ovad093. Synergistic action of indole-3-carbinol with membrane-active agents against multidrug-resistant Gram-negative bacteria. Wang TP(1), Yeh TH(2), Lo CC(3), Lin KH(4), Huang MH(4), Lo HR(4). Author information: (1)Departm

Combination of xanthohumol and phenethyl isothiocyanate inhibits NF-κB and activates Nrf2 in pancreatic cancer cells.

3. Toxicol In Vitro. 2020 Jun;65:104799. doi: 10.1016/j.tiv.2020.104799. Epub 2020 Feb 15. Combination of xanthohumol and phenethyl isothiocyanate inhibits NF-κB and activates Nrf2 in pancreatic cancer cells. Krajka-Kuźniak V(1), Cykowiak M(2), Szaefer H(2), Kleszcz R(2), Baer-Dubowska W(2). A

Co-treatment with indole-3-carbinol and resveratrol modify porcine CYP1A and CYP3A activities and expression.

4. Xenobiotica. 2018 Mar;48(3):232-240. doi: 10.1080/00498254.2017.1300708. Epub 2017 Mar 19. Co-treatment with indole-3-carbinol and resveratrol modify porcine CYP1A and CYP3A activities and expression. Zamaratskaia G(1)(2), Thøgersen R(3), Čandek-Potokar M(4)(5), Rasmussen MK(3). Author infor

Indole-3- carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic study.

5. Sci Rep. 2016 Sep 9;6:32733. doi: 10.1038/srep32733. Indole-3- carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic study. Abdelmageed MM(1), El-Naga RN(2), El-Demerdash E(2)(3), Elmazar MM(1). Author information: (1)Department of Pharmacology and Toxicolo

Cooperative antiproliferative signaling by aspirin and indole-3-carbinol targets microphthalmia-associated transcription factor gene expression and promoter activity in human melanoma cells.

6. Cell Biol Toxicol. 2016 Apr;32(2):103-19. doi: 10.1007/s10565-016-9321-5. Epub 2016 Apr 7. Cooperative antiproliferative signaling by aspirin and indole-3-carbinol targets microphthalmia-associated transcription factor gene expression and promoter activity in human melanoma cells. Poindexter

Anti-cancer and cardioprotective effects of indol-3-carbinol in doxorubicin-treated mice.

7. J Infect Chemother. 2016 Jan;22(1):36-43. doi: 10.1016/j.jiac.2015.10.001. Epub 2015 Nov 19. Anti-cancer and cardioprotective effects of indol-3-carbinol in doxorubicin-treated mice. Adwas AA(1), Elkhoely AA(2), Kabel AM(3), Abdel-Rahman MN(4), Eissa AA(2). Author information: (1)Pharmacolog

Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances.

8. Clin Cancer Res. 2016 Jan 1;22(1):134-45. doi: 10.1158/1078-0432.CCR-15-0736. Epub 2015 Aug 31. Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances. Perez-Chacon G(1), Martinez-Lap

Inhibition of Testosterone Aromatization by the Indole-3-carbinol Derivative CTet in CYP19A1-overexpressing MCF-7 Breast Cancer Cells.

9. Anticancer Agents Med Chem. 2015;15(7):896-904. doi: 10.2174/1871520615666150121123053. Inhibition of Testosterone Aromatization by the Indole-3-carbinol Derivative CTet in CYP19A1-overexpressing MCF-7 Breast Cancer Cells. De Santi M(1), Carloni E, Galluzzi L, Diotallevi A, Lucarini S, Magnan

Indole-3-carbinol (I3C) increases apoptosis, represses growth of cancer cells, and enhances adenovirus-mediated oncolysis.

10. Cancer Biol Ther. 2014 Sep;15(9):1256-67. doi: 10.4161/cbt.29690. Epub 2014 Jun 27. Indole-3-carbinol (I3C) increases apoptosis, represses growth of cancer cells, and enhances adenovirus-mediated oncolysis. Chen L(1), Cheng PH(2), Rao XM(3), McMasters KM(4), Zhou HS(5). Author information: