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Does l-citrulline supplementation and watermelon intake reduce blood pressure in middle-aged and older adults? A systematic review and meta-analysis of randomized controlled trials.

1. Clin Nutr ESPEN. 2025 Oct;69:653-664. doi: 10.1016/j.clnesp.2025.07.1130. Epub 2025 Aug 9. Does l-citrulline supplementation and watermelon intake reduce blood pressure in middle-aged and older adults? A systematic review and meta-analysis of randomized controlled trials. Luo P(1), Chen J(2)

Effects of Different Dietary Supplements on Swimming Performance: A Systematic Review and Network Meta-Analysis.

2. Nutrients. 2024 Dec 26;17(1):33. doi: 10.3390/nu17010033. Effects of Different Dietary Supplements on Swimming Performance: A Systematic Review and Network Meta-Analysis. Huang D(1)(2), Wang X(1), Takagi H(3), Mo S(4), Wang Z(5), Chow DH(2), Huang B(5). Author information: (1)School of Physi

Nutraceutical interventions for erectile dysfunction: a systematic review and network meta-analysis.

3. J Sex Med. 2024 Oct 31;21(11):1054-1063. doi: 10.1093/jsxmed/qdae123. Nutraceutical interventions for erectile dysfunction: a systematic review and network meta-analysis. Barbonetti A(1), Tienforti D(1), Antolini F(1), Spagnolo L(1), Cavallo F(2), Di Pasquale AB(3), Maggi M(4)(5)(6), Corona G

Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use.

4. Nutrients. 2023 Aug 22;15(17):3677. doi: 10.3390/nu15173677. Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use. Petre GC(1), Francini-Pesenti F(2), Vitagliano A(3), Grande G(1), Ferlin A(1), Garolla A(1). Author inf

Watermelon consumption decreases risk factors of cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials.

5. Diabetes Res Clin Pract. 2023 Aug;202:110801. doi: 10.1016/j.diabres.2023.110801. Epub 2023 Jun 25. Watermelon consumption decreases risk factors of cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials. Karimi E(1), Abaj F(2), Gholizadeh M(3), Asbaghi

The Potential Role of Arginine Supplements on Erectile Dysfunction: A Systemic Review and Meta-Analysis.

6. J Sex Med. 2019 Feb;16(2):223-234. doi: 10.1016/j.jsxm.2018.12.002. The Potential Role of Arginine Supplements on Erectile Dysfunction: A Systemic Review and Meta-Analysis. Rhim HC(1), Kim MS(1), Park YJ(2), Choi WS(2), Park HK(2), Kim HG(2), Kim A(2), Paick SH(3). Author information: (1)Kor

Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis.

7. Nutrients. 2018 Dec 20;11(1):15. doi: 10.3390/nu11010015. Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis. Rodrigues-Krause J(1), Krause M(2), Rocha IMGD(3), Umpierre D

Effect of L-arginine supplementation on blood pressure in pregnant women: a meta-analysis of placebo-controlled trials.

8. Hypertens Pregnancy. 2013;32(1):32-41. doi: 10.3109/10641955.2012.697952. Epub 2012 Sep 7. Effect of L-arginine supplementation on blood pressure in pregnant women: a meta-analysis of placebo-controlled trials. Zhu Q(1), Yue X, Tian QY, Saren G, Wu MH, Zhang Y, Liu TT. Author information: (1

Effect of Perioperative Supplementation with Arginine and Omega-3 on Postoperative Complications in Patients Undergoing Gastrointestinal Cancer Surgery: A Pilot Open-Label Randomized Controlled Trial.

9. Nutrients. 2026 Feb 16;18(4):651. doi: 10.3390/nu18040651. Effect of Perioperative Supplementation with Arginine and Omega-3 on Postoperative Complications in Patients Undergoing Gastrointestinal Cancer Surgery: A Pilot Open-Label Randomized Controlled Trial. Sakhri S(1), Othman RB(2)(3)(4),

L-ornithine supplementation in periodontitis treatment yields greater benefits than L-arginine after one year: Part II of a randomized controlled pilot study.

10. Complement Ther Med. 2025 Sep;92:103202. doi: 10.1016/j.ctim.2025.103202. Epub 2025 Jul 2. L-ornithine supplementation in periodontitis treatment yields greater benefits than L-arginine after one year: Part II of a randomized controlled pilot study. Shynkevych VI(1), Kolomiiets SV(2), Udalts

Azetukalner, a Novel KV7 Potassium Channel Opener, in Adults With Major Depressive Disorder: A Randomized Clinical Trial.

11. JAMA Netw Open. 2025 May 1;8(5):e2514278. doi: 10.1001/jamanetworkopen.2025.14278. Azetukalner, a Novel KV7 Potassium Channel Opener, in Adults With Major Depressive Disorder: A Randomized Clinical Trial. Butterfield NN(1), Luzon Rosenblut C(1), Fava M(2), Correll CU(3)(4)(5), Rothschild AJ

Arginine Therapy for Pain in Sickle Cell Disease: A Phase-2 Randomized, Placebo-Controlled Trial.

12. Am J Hematol. 2025 Jul;100(7):1119-1131. doi: 10.1002/ajh.27692. Epub 2025 Apr 24. Arginine Therapy for Pain in Sickle Cell Disease: A Phase-2 Randomized, Placebo-Controlled Trial. Morris CR(1)(2)(3), Hatabah D(1), Korman R(1), Gillespie S(1), Bakshi N(4), Brown LA(1), Harris F(1), Leake D(

Investigation of the effect of nitrate and L-arginine intake on aerobic, anaerobic performance, balance, agility, and recovery in elite taekwondo athletes.

13. J Int Soc Sports Nutr. 2025 Dec;22(1):2445609. doi: 10.1080/15502783.2024.2445609. Epub 2024 Dec 23. Investigation of the effect of nitrate and L-arginine intake on aerobic, anaerobic performance, balance, agility, and recovery in elite taekwondo athletes. Kavcı Z(1), Ozan M(2), Buzdağlı Y(

Malate or Not? Acute Effects of L-Citrulline Versus Citrulline Malate on Neuromuscular Performance in Young, Trained Adults: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial.

14. Int J Sport Nutr Exerc Metab. 2024 Dec 11;35(2):89-98. doi: 10.1123/ijsnem.2024-0006. Print 2025 Mar 1. Malate or Not? Acute Effects of L-Citrulline Versus Citrulline Malate on Neuromuscular Performance in Young, Trained Adults: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial.

Effects of Acute Citrulline Malate Supplementation on CrossFit(®) Exercise Performance: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study.

15. Nutrients. 2024 Sep 24;16(19):3235. doi: 10.3390/nu16193235. Effects of Acute Citrulline Malate Supplementation on CrossFit(®) Exercise Performance: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study. Devrim-Lanpir A(1)(2), Ihász F(3), Demcsik M(3), Horváth AC(3), Góczán P(3),

Novel multi-modal methodology to investigate placebo response in major depressive disorder.

32. J Affect Disord. 2025 Jan 1;368:1-7. doi: 10.1016/j.jad.2024.08.226. Epub 2024 Sep 2. Novel multi-modal methodology to investigate placebo response in major depressive disorder. Cusin C(1), Dillon DG(2), Belleau E(2), Normandin MD(3), Petibon Y(3), El-Fakri G(3), Dhaynaut M(3), Hooker J(3),

Association of rheumatoid factor, anti-citrullinated protein antibodies and shared epitope with clinical response to initial treatment in patients with early rheumatoid arthritis: data from a randomised controlled trial.

25. Ann Rheum Dis. 2024 Nov 14;83(12):1657-1665. doi: 10.1136/ard-2024-226024. Association of rheumatoid factor, anti-citrullinated protein antibodies and shared epitope with clinical response to initial treatment in patients with early rheumatoid arthritis: data from a randomised controlled tria

The effect of a multicomponent oral care regimen on gingival inflammation: A randomized controlled clinical trial.

46. J Periodontol. 2024 Apr;95(4):350-359. doi: 10.1002/JPER.23-0361. Epub 2023 Oct 4. The effect of a multicomponent oral care regimen on gingival inflammation: A randomized controlled clinical trial. do Amaral GCLS(1), Hassan MA(1), Saraiva L(1), Nakao LYS(1), Holzhausen M(1), Malheiros ZM(2)

Synergistic effects of antibiotics and efflux pump inhibitors on multidrug-resistant Escherichia coli and Klebsiella pneumoniae.

47. J Appl Microbiol. 2025 Jul 1;136(7):lxaf169. doi: 10.1093/jambio/lxaf169. Synergistic effects of antibiotics and efflux pump inhibitors on multidrug-resistant Escherichia coli and Klebsiella pneumoniae. Devi BT(1), Aditya V(1), Kini S(2), Kumar BK(1), Deekshit VK(1). Author information: (1)N

CARM1-Mediated MAP2K4 Methylation Potentiates the Oncogenic Functions of MAP2K4 and Constitutes a Targetable Dependency in Triple-Negative Breast Cancer.

31. Cancer Res. 2025 Aug 15;85(16):3072-3088. doi: 10.1158/0008-5472.CAN-24-3476. CARM1-Mediated MAP2K4 Methylation Potentiates the Oncogenic Functions of MAP2K4 and Constitutes a Targetable Dependency in Triple-Negative Breast Cancer. Kim EJ(1)(2), Wang Y(1)(2), Chen YL(1)(2), Ma M(3), Liu P(2)(

Self-synergy antinociceptive effect of diclofenac: effect of peripheral inhibition of nitric oxide synthase.

45. Behav Pharmacol. 2025 Aug 1;36(5):258-264. doi: 10.1097/FBP.0000000000000824. Epub 2025 Apr 2. Self-synergy antinociceptive effect of diclofenac: effect of peripheral inhibition of nitric oxide synthase. Torres-López JE(1), Martínez-Martínez M, Parra-Flores LI. Author information: (1)Divisi

Effects of melatonin on the pharmacokinetics and amino acid metabolism profile of vigabatrin in rats.

10. Toxicol Appl Pharmacol. 2025 Mar;496:117247. doi: 10.1016/j.taap.2025.117247. Epub 2025 Jan 28. Effects of melatonin on the pharmacokinetics and amino acid metabolism profile of vigabatrin in rats. Zheng Q(1), Xu SL(2), Guo XL(2), Wang CY(2), Ma MD(2), Ge JF(3). Author information: (1)Schoo

A new therapeutic strategy for infectious diseases against intracellular multidrug-resistant bacteria.

35. J Control Release. 2024 Nov;375:467-477. doi: 10.1016/j.jconrel.2024.09.028. Epub 2024 Sep 20. A new therapeutic strategy for infectious diseases against intracellular multidrug-resistant bacteria. Wang ZJ(1), Zhu YY(1), Bai LY(1), Tang DM(1), Zhou ZS(1), Wei MZ(1), He JB(1), Yu-Duan(1), Lu

Tumor-Targeted cRGD-Coated Liposomes Encapsulating Optimized Synergistic Cepharanthine and IR783 for Chemotherapy and Photothermal Therapy.

39. Int J Nanomedicine. 2024 Jun 19;19:6145-6160. doi: 10.2147/IJN.S457008. eCollection 2024. Tumor-Targeted cRGD-Coated Liposomes Encapsulating Optimized Synergistic Cepharanthine and IR783 for Chemotherapy and Photothermal Therapy. Wu Y(#)(1)(2)(3), Zeng C(#)(1)(2)(3), Lv J(1)(2)(3), Li H(1)(2

An Albumin-Based Therapeutic Nanosystem for Photosensitizer/Protein Co-Delivery to Realize Synergistic Cancer Therapy.

36. ACS Appl Bio Mater. 2021 Jun 21;4(6):4946-4952. doi: 10.1021/acsabm.1c00233. Epub 2021 Jun 10. An Albumin-Based Therapeutic Nanosystem for Photosensitizer/Protein Co-Delivery to Realize Synergistic Cancer Therapy. Ai SL(1), Wang CX(1), Peng Y(2), Tu Y(3), Lei JJ(4), Xu C(1), Ren XH(1), Cheng

Antinociceptive Synergism of Pomegranate Peel Extract and Acetylsalicylic Acid in an Animal Pain Model.

14. Molecules. 2021 Sep 7;26(18):5434. doi: 10.3390/molecules26185434. Antinociceptive Synergism of Pomegranate Peel Extract and Acetylsalicylic Acid in an Animal Pain Model. Guerrero-Solano JA(1), Bautista M(1), Velázquez-González C(1), De la O-Arciniega M(1), González-Olivares LG(2), Fernández

Targeting hyperactive TGFBR2 for treating MYOCD deficient lung cancer.

41. Theranostics. 2021 May 3;11(13):6592-6606. doi: 10.7150/thno.59816. eCollection 2021. Targeting hyperactive TGFBR2 for treating MYOCD deficient lung cancer. Zhou Q(1), Chen W(1), Fan Z(1), Chen Z(1), Liang J(1), Zeng G(1), Liu L(1), Liu W(1), Yang T(1), Cao X(2), Yu B(3), Xu M(4), Chen YG(5)

Chitosan coated synergistically engineered nanoemulsion of Ropinirole and nigella oil in the management of Parkinson's disease: Formulation perspective and In vitro and In vivo assessment.

45. Int J Biol Macromol. 2021 Jan 15;167:605-619. doi: 10.1016/j.ijbiomac.2020.11.207. Epub 2020 Dec 2. Chitosan coated synergistically engineered nanoemulsion of Ropinirole and nigella oil in the management of Parkinson's disease: Formulation perspective and In vitro and In vivo assessment. Ne

Identification of the major allergens of Charybdis feriatus (red crab) and its cross-reactivity with Portunus pelagicus (blue crab).

37. Asian Pac J Allergy Immunol. 2012 Dec;30(4):285-93. Identification of the major allergens of Charybdis feriatus (red crab) and its cross-reactivity with Portunus pelagicus (blue crab). Misnan R(1), Murad S, Yadzir ZH, Abdullah N. Author information: (1)Department of Biology, Faculty of Scien

Efficacy of Desmopressin for Post-Kidney Biopsy Bleeding Complications Prevention: A Systematic Review With Frequentist and Bayesian Meta-Analysis.

6. Nephrology (Carlton). 2026 Jan;31(1):e70164. doi: 10.1111/nep.70164. Efficacy of Desmopressin for Post-Kidney Biopsy Bleeding Complications Prevention: A Systematic Review With Frequentist and Bayesian Meta-Analysis. Chen JJ(1)(2), Lee TH(3), Lai PC(4), Tu YK(5), Hsu HH(1)(2), Yang HY(1)(2)(6)