L-테아닌

The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.

1. Sleep Med Rev. 2025 Jun;81:102076. doi: 10.1016/j.smrv.2025.102076. Epub 2025 Feb 25. The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis. Bulman A(1), D'Cunha NM(2), Marx W(3), Turner M(4), McKune A(5), Naumovski N(6). Author information: (1)Facult

Performance-enhancing effects of caffeine and L-Theanine among Iranian elite wrestlers: a focus on cognitive and specific physical performance.

2. J Int Soc Sports Nutr. 2025 Dec;22(1):2564238. doi: 10.1080/15502783.2025.2564238. Epub 2025 Sep 22. Performance-enhancing effects of caffeine and L-Theanine among Iranian elite wrestlers: a focus on cognitive and specific physical performance. Razazan R(1), Hemmatinafar M(1), Imanian B(1), J

High-dose L-theanine-caffeine combination improves neurobehavioural and neurophysiological measures of selective attention in acutely sleep-deprived young adults: a double-blind, placebo-controlled crossover study.

3. Br J Nutr. 2025 Aug 14;134(3):195-204. doi: 10.1017/S0007114525104169. Epub 2025 Aug 12. High-dose L-theanine-caffeine combination improves neurobehavioural and neurophysiological measures of selective attention in acutely sleep-deprived young adults: a double-blind, placebo-controlled crosso

Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.

4. Nutr Neurosci. 2025 Apr;28(4):471-480. doi: 10.1080/1028415X.2024.2383080. Epub 2024 Jul 25. Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study. Karunaratne UW(1), Dassanayake TL(1)

Impact of L-theanine and L-tyrosine on markers of stress and cognitive performance in response to a virtual reality based active shooter training drill.

5. Stress. 2024 Jan;27(1):2375588. doi: 10.1080/10253890.2024.2375588. Epub 2024 Jul 8. Impact of L-theanine and L-tyrosine on markers of stress and cognitive performance in response to a virtual reality based active shooter training drill. McAllister MJ(1), Martaindale MH(2), Dillard CC(1), Mc

Caffeine Gum Improves Reaction Time but Reduces Composure Versus Placebo During the Extra-Time Period of Simulated Soccer Match-Play in Male Semiprofessional Players.

6. Int J Sport Nutr Exerc Metab. 2024 Jun 25;34(5):286-297. doi: 10.1123/ijsnem.2023-0220. Print 2024 Sep 1. Caffeine Gum Improves Reaction Time but Reduces Composure Versus Placebo During the Extra-Time Period of Simulated Soccer Match-Play in Male Semiprofessional Players. Field A(1), Corr L(

Effect of a nutraceutical combination on sleep quality among people with impaired sleep: a randomised, placebo-controlled trial.

7. Sci Rep. 2024 Apr 5;14(1):8062. doi: 10.1038/s41598-024-58661-z. Effect of a nutraceutical combination on sleep quality among people with impaired sleep: a randomised, placebo-controlled trial. Gutiérrez-Romero SA(1), Torres-Narváez ES(1), Zamora-Gómez AC(2), Castillo-Castillo S(3), Latorre-V

Effect of single or combined caffeine and L-Theanine supplementation on shooting and cognitive performance in elite curling athletes: a double-blind, placebo-controlled study.

8. J Int Soc Sports Nutr. 2023 Dec;20(1):2267536. doi: 10.1080/15502783.2023.2267536. Epub 2023 Oct 10. Effect of single or combined caffeine and L-Theanine supplementation on shooting and cognitive performance in elite curling athletes: a double-blind, placebo-controlled study. Yilmaz U(1), Bu

[Clinical evaluation of the efficacy of innovative spread of a given fatty acid composition enriched by adaptogens].

9. Vopr Pitan. 2023;92(4):104-113. doi: 10.33029/0042-8833-2023-92-4-104-113. Epub 2023 Jun 30. [Clinical evaluation of the efficacy of innovative spread of a given fatty acid composition enriched by adaptogens]. [Article in Russian] Pilipenko VI(1), Isakov VA(1), Morozov SV(2), Sasunova AN(1),

L-Theanine adjunct to risperidone in the treatment of chronic schizophrenia inpatients: a randomized, double-blind, placebo-controlled clinical trial.

10. Psychopharmacology (Berl). 2023 Dec;240(12):2631-2640. doi: 10.1007/s00213-023-06458-9. Epub 2023 Sep 12. L-Theanine adjunct to risperidone in the treatment of chronic schizophrenia inpatients: a randomized, double-blind, placebo-controlled clinical trial. Shamabadi A(#)(1), Fattollahzadeh-N

Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.

11. Nutrients. 2023 May 19;15(10):2377. doi: 10.3390/nu15102377. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems. Imafuku F(1), Yamamoto K(1), Tanaka E(1), Aoki R(1), Nishino S(2). Author information: (1)Ezaki Glico Co.,

Spectral analysis and computational simulation to investigate the synergistic mechanism of L-theanine and epigallocatechin gallate in inhibiting α-glucosidase activity.

12. Food Chem. 2025 Oct 1;488:144858. doi: 10.1016/j.foodchem.2025.144858. Epub 2025 May 21. Spectral analysis and computational simulation to investigate the synergistic mechanism of L-theanine and epigallocatechin gallate in inhibiting α-glucosidase activity. Hao Z(1), Li Z(1), Ma Z(1), Liu X

Exploring the effect of L-theanine synergised with EGCG on starch digestibility in ultrasonic field from different perspectives.

13. Food Res Int. 2025 Feb;202:115805. doi: 10.1016/j.foodres.2025.115805. Epub 2025 Jan 20. Exploring the effect of L-theanine synergised with EGCG on starch digestibility in ultrasonic field from different perspectives. Hao Z(1), Li Z(1), Zhou Q(2), Ma Z(1), Wang Y(1), Lv J(1), Xu H(2), Li D(2

Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.

14. Nutrients. 2021 Nov 17;13(11):4120. doi: 10.3390/nu13114120. Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate. Lin L(1)(2)(3), Zeng L(4), Liu A(1)(2)(3), Yuan D(1)(2)(3), Peng Y(1)(2)(3),

Effects of L-theanine-caffeine combination on sustained attention and inhibitory control among children with ADHD: a proof-of-concept neuroimaging RCT.

15. Sci Rep. 2020 Aug 4;10(1):13072. doi: 10.1038/s41598-020-70037-7. Effects of L-theanine-caffeine combination on sustained attention and inhibitory control among children with ADHD: a proof-of-concept neuroimaging RCT. Kahathuduwa CN(1)(2)(3), Wakefield S(4)(5), West BD(5), Blume J(5), Dassana

GABA and l-theanine mixture decreases sleep latency and improves NREM sleep.

11. Pharm Biol. 2019 Dec;57(1):65-73. doi: 10.1080/13880209.2018.1557698. GABA and l-theanine mixture decreases sleep latency and improves NREM sleep. Kim S(1), Jo K(1), Hong KB(2), Han SH(3), Suh HJ(4). Author information: (1)a Department of Integrated Biomedical and Life Sciences , Graduate Sch

More than just caffeine: psychopharmacology of methylxanthine interactions with plant-derived phytochemicals.

4. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:263-274. doi: 10.1016/j.pnpbp.2018.09.005. Epub 2018 Sep 10. More than just caffeine: psychopharmacology of methylxanthine interactions with plant-derived phytochemicals. Schuster J(1), Mitchell ES(2). Author information: (1)Swammerdam

Effects of a Multi-Ingredient Energy Supplement on Cognitive Performance and Cerebral-Cortical Activation.

23. J Diet Suppl. 2019;16(2):129-140. doi: 10.1080/19390211.2018.1440686. Epub 2018 Mar 13. Effects of a Multi-Ingredient Energy Supplement on Cognitive Performance and Cerebral-Cortical Activation. Daou M(1), Sassi JM(1), Miller MW(1), Gonzalez AM(2). Author information: (1)a School of Kinesio

l-Theanine and caffeine improve target-specific attention to visual stimuli by decreasing mind wandering: a human functional magnetic resonance imaging study.

42. Nutr Res. 2018 Jan;49:67-78. doi: 10.1016/j.nutres.2017.11.002. Epub 2017 Nov 16. l-Theanine and caffeine improve target-specific attention to visual stimuli by decreasing mind wandering: a human functional magnetic resonance imaging study. Kahathuduwa CN(1), Dhanasekara CS(2), Chin SH(2), D

The synergistic potential of various teas, herbs and therapeutic drugs in health improvement: a review.

24. J Sci Food Agric. 2017 Nov;97(14):4679-4689. doi: 10.1002/jsfa.8472. Epub 2017 Jul 27. The synergistic potential of various teas, herbs and therapeutic drugs in health improvement: a review. Malongane F(1), McGaw LJ(2), Mudau FN(3). Author information: (1)Department Life and Consumer Scienc

Caffeine and theanine exert opposite effects on attention under emotional arousal.

30. Can J Physiol Pharmacol. 2017 Jan;95(1):93-100. doi: 10.1139/cjpp-2016-0498. Caffeine and theanine exert opposite effects on attention under emotional arousal. Giles GE(1)(1), Mahoney CR(1)(1), Brunyé TT(1)(1), Taylor HA(1)(1), Kanarek RB(1)(1). Author information: (1)Department of Psycholo

Dietary supplementation with Lactium and L-theanine alleviates sleep disturbance in adults: a double-blind, randomized, placebo-controlled clinical study.

45. Front Nutr. 2024 Jun 17;11:1419978. doi: 10.3389/fnut.2024.1419978. eCollection 2024. Dietary supplementation with Lactium and L-theanine alleviates sleep disturbance in adults: a double-blind, randomized, placebo-controlled clinical study. Lim SE(#)(1), Kim HS(#)(1), Lee S(1), Kang EY(2), L

Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials.

50. Nutr Neurosci. 2026 Feb;29(2):224-238. doi: 10.1080/1028415X.2025.2556925. Epub 2025 Nov 1. Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials. Cotter J(1), Caddick CE(2), Harper JL(2), Ebajemito JK(2). Author information: (1)Research and Deve

Efficiency of Different Supplements in Alleviating Symptoms of ADHD with or Without the Use of Stimulants: A Systematic Review.

31. Nutrients. 2025 Apr 28;17(9):1482. doi: 10.3390/nu17091482. Efficiency of Different Supplements in Alleviating Symptoms of ADHD with or Without the Use of Stimulants: A Systematic Review. Al Shahab S(1), Al Balushi R(1), Qambar A(1), Abdulla R(1), Qader M(1), Abdulla S(1), Jahrami H(1)(2).

Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

24. Nutr Rev. 2025 Oct 1;83(10):1873-1891. doi: 10.1093/nutrit/nuaf054. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

The effects of L-theanine supplementation on the outcomes of patients with mental disorders: a systematic review.

29. BMC Psychiatry. 2024 Dec 4;24(1):886. doi: 10.1186/s12888-024-06285-y. The effects of L-theanine supplementation on the outcomes of patients with mental disorders: a systematic review. Moshfeghinia R(1)(2)(3), Sanaei E(4), Mostafavi S(5), Assadian K(5), Sanaei A(4), Ayano G(6). Author infor

Association between sleep pattern and pharmacological treatment in children with attention deficit disorder with hyperactivity: a systematic review.

43. Rev Paul Pediatr. 2023 May 29;41:e2022065. doi: 10.1590/1984-0462/2023/41/2022065. eCollection 2023. Association between sleep pattern and pharmacological treatment in children with attention deficit disorder with hyperactivity: a systematic review. Rocha NS(1), Correa RDESA(1), Dias ACM(1),

Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.

21. Pharmacol Res. 2022 May;179:106204. doi: 10.1016/j.phrs.2022.106204. Epub 2022 Apr 1. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis. Zhang W(1), Yan Y(1), Wu Y(1), Yang H(1), Zhu P(1), Yan F(1), Zhao R(1), Tian P(1), Wang T(2), Fan Q(3), Su Z(4)

The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.

49. Plant Foods Hum Nutr. 2020 Mar;75(1):12-23. doi: 10.1007/s11130-019-00771-5. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review. Williams JL(1)(2), Everett JM(1), D'Cunha NM(1)(2), Sergi D(3), Georgousopoulou EN(

Botanicals and phytochemicals active on cognitive decline: The clinical evidence.

50. Pharmacol Res. 2018 Apr;130:204-212. doi: 10.1016/j.phrs.2017.12.029. Epub 2017 Dec 28. Botanicals and phytochemicals active on cognitive decline: The clinical evidence. Cicero AFG(1), Fogacci F(1), Banach M(2). Author information: (1)Department of Medical and Surgical Sciences, Alma Mater