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Interventions for central serous chorioretinopathy: a network meta-analysis.

1. Cochrane Database Syst Rev. 2025 Jun 16;6(6):CD011841. doi: 10.1002/14651858.CD011841.pub3. Interventions for central serous chorioretinopathy: a network meta-analysis. Lange CA(1)(2), Qureshi R(3)(4), Pauleikhoff L(2)(5). Author information: (1)Department of Ophthalmology, St Franziskus Hosp

Lutein and zeaxanthin for reducing morbidity and mortality in preterm infants.

2. Cochrane Database Syst Rev. 2025 Apr 28;4(4):CD012178. doi: 10.1002/14651858.CD012178.pub2. Lutein and zeaxanthin for reducing morbidity and mortality in preterm infants. Choo YM(1), Yip KX(2), Fiander M(3), Ahmad Kamar A(1), Kamalden TA(4), Tan K(5)(6), Lai NM(7). Author information: (1)Dep

Effect of Antioxidant Supplementation on Macular Pigment Optical Density and Visual Functions: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.

3. Adv Nutr. 2024 May;15(5):100216. doi: 10.1016/j.advnut.2024.100216. Epub 2024 Apr 4. Effect of Antioxidant Supplementation on Macular Pigment Optical Density and Visual Functions: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Hu W(1), Seah V(1), Huang V(1), K

Not all carotenoids can reduce the risk of gastric cancer: a systematic review with meta-analysis.

4. BMC Gastroenterol. 2024 Jan 29;24(1):51. doi: 10.1186/s12876-024-03139-5. Not all carotenoids can reduce the risk of gastric cancer: a systematic review with meta-analysis. Han W(1)(2), Zhang W(2), Ren X(3)(4). Author information: (1)Department of General Surgery, Lanzhou University Second Ho

Moderators of Caffeine's Effects on Jumping Performance in Females: A Systematic Review and Meta-Analysis.

5. J Am Nutr Assoc. 2024 Jan;43(1):92-100. doi: 10.1080/27697061.2023.2212740. Epub 2023 May 16. Moderators of Caffeine's Effects on Jumping Performance in Females: A Systematic Review and Meta-Analysis. Grgic J(1), Varovic D(2). Author information: (1)Institute for Health and Sport, Victoria U

Effect of xanthophyll-rich food and supplement intake on visual outcomes in healthy adults and those with eye disease: a systematic review, meta-analysis, and meta-regression of randomized controlled trials.

6. Nutr Rev. 2023 Dec 11;82(1):34-46. doi: 10.1093/nutrit/nuad037. Effect of xanthophyll-rich food and supplement intake on visual outcomes in healthy adults and those with eye disease: a systematic review, meta-analysis, and meta-regression of randomized controlled trials. Hu W(1), Shankar P(1)

The effect of lutein and Zeaxanthine on dyslipidemia: A meta-analysis study.

7. Prostaglandins Other Lipid Mediat. 2023 Feb;164:106691. doi: 10.1016/j.prostaglandins.2022.106691. Epub 2022 Nov 3. The effect of lutein and Zeaxanthine on dyslipidemia: A meta-analysis study. Ghasemi F(1), Navab F(2), Rouhani MH(2), Amini P(1), Shokri-Mashhadi N(3). Author information: (1)Nu

The Effect of Dietary Supplementations on Delaying the Progression of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis.

8. Nutrients. 2022 Oct 13;14(20):4273. doi: 10.3390/nu14204273. The Effect of Dietary Supplementations on Delaying the Progression of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis. Csader S(1), Korhonen S(2), Kaarniranta K(3)(4), Schwab U(1)(5). Author information: (1)S

Efficacy of different nutrients in age-related macular degeneration: A systematic review and network meta-analysis.

9. Semin Ophthalmol. 2022 May 19;37(4):515-523. doi: 10.1080/08820538.2021.2022165. Epub 2022 Jan 7. Efficacy of different nutrients in age-related macular degeneration: A systematic review and network meta-analysis. Li SS(1), Wang HH(2), Zhang D(1). Author information: (1)Department of Ophthal

The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis.

10. Adv Nutr. 2021 Dec 1;12(6):2244-2254. doi: 10.1093/advances/nmab071. The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis. Wilson LM(1), Tharmarajah S(1), Jia Y(2), Semba RD(3)(4), Schaumberg DA(5)(6), Robinson KA(1)(2). Auth

Effects of Randomized Multivitamin Supplementation on Carotenoids and α-Tocopherol in the COcoa Supplement and Multivitamin Outcomes Study.

11. J Acad Nutr Diet. 2026 May;126(5):156299. doi: 10.1016/j.jand.2026.156299. Epub 2026 Jan 24. Effects of Randomized Multivitamin Supplementation on Carotenoids and α-Tocopherol in the COcoa Supplement and Multivitamin Outcomes Study. Christopher CN(1), Erdman JW Jr(2), Kim E(3), Black M(2), R

New infant formulas for healthy term infants: A randomized, controlled, double-blind, multicenter, non-inferiority design safety study.

12. PLoS One. 2025 Dec 17;20(12):e0336689. doi: 10.1371/journal.pone.0336689. eCollection 2025. New infant formulas for healthy term infants: A randomized, controlled, double-blind, multicenter, non-inferiority design safety study. Fleming SA(1), Flunkert S(2), Kvistgaard AS(3), McGrath J(4), Gl

Effect of Lutein Ester Supplement on Choroidal Thickness in Children: A Randomized Controlled Trial.

13. Transl Vis Sci Technol. 2025 Dec 1;14(12):7. doi: 10.1167/tvst.14.12.7. Effect of Lutein Ester Supplement on Choroidal Thickness in Children: A Randomized Controlled Trial. Li T(1)(2)(3), Li J(1)(4), Deng C(5), Yang F(1)(2)(3), Ran J(1)(2)(3), Wang E(6), Qin W(7), Yang M(5), Li X(8), Li L(7)

Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled trial.

14. Am J Clin Nutr. 2025 Nov;122(5):1289-1297. doi: 10.1016/j.ajcnut.2025.08.012. Epub 2025 Aug 27. Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled tri

Enhanced Oral Bioavailability of Lutein and Zeaxanthin via a Self-Emulsifying Delivery System: A Randomized, Double-Blind Cross-Over Study.

15. J Med Food. 2025 Aug;28(8):824-832. doi: 10.1089/jmf.2025.k.0060. Epub 2025 Jul 2. Enhanced Oral Bioavailability of Lutein and Zeaxanthin via a Self-Emulsifying Delivery System: A Randomized, Double-Blind Cross-Over Study. Choe BS(1), C A(2), Mk P(3), Kim J(4), Baek KS(4), Park YK(1). Autho

Neuroprotective nutrients in pregnancy and infant brain function.

5. Clin Nutr ESPEN. 2025 Aug;68:417-422. doi: 10.1016/j.clnesp.2025.05.030. Epub 2025 May 22. Neuroprotective nutrients in pregnancy and infant brain function. Christifano DN(1), Liao K(2), Mathis NB(3), Carlson SE(3), Colombo J(4), Chollet-Hinton L(5), Gustafson KM(2). Author information: (1)D

Effect of lutein supplementation on blood lipids and advanced glycation end products in adults with central obesity: a double-blind randomized controlled trial.

21. Food Funct. 2025 Mar 3;16(5):2096-2107. doi: 10.1039/d4fo05578k. Effect of lutein supplementation on blood lipids and advanced glycation end products in adults with central obesity: a double-blind randomized controlled trial. Zhou J(1)(2)(3), Wang S(1)(2)(3), Wang Q(1)(2)(3), Zhao R(1)(2)(3)

Effect of Dietary Supplementation with Lutein, Zeaxanthin, and Elderberries on Dry Eye Disease (DED) and Immunity: A Randomized Controlled Trial.

22. Nutrients. 2024 Dec 18;16(24):4366. doi: 10.3390/nu16244366. Effect of Dietary Supplementation with Lutein, Zeaxanthin, and Elderberries on Dry Eye Disease (DED) and Immunity: A Randomized Controlled Trial. Goh KM(1)(2), Tan ESS(3), Lim CSY(4), Tan PY(5), Biswas S(6), Lew LA(2)(7), Tan CK(3)

Beneficial Effects of Micronutrient Supplementation in Restoring the Altered Microbiota and Gut-Retina Axis in Patients with Neovascular Age-Related Macular Degeneration-A Randomized Clinical Trial.

46. Nutrients. 2024 Nov 20;16(22):3971. doi: 10.3390/nu16223971. Beneficial Effects of Micronutrient Supplementation in Restoring the Altered Microbiota and Gut-Retina Axis in Patients with Neovascular Age-Related Macular Degeneration-A Randomized Clinical Trial. Baldi S(1), Pagliai G(1), Di Glo

Pistachio Consumption Increases Macular Pigment Optical Density in Healthy Adults: A Randomized Controlled Trial.

48. J Nutr. 2025 Jan;155(1):168-174. doi: 10.1016/j.tjnut.2024.10.022. Epub 2024 Oct 18. Pistachio Consumption Increases Macular Pigment Optical Density in Healthy Adults: A Randomized Controlled Trial. Scott TM(1), Ogunbodede O(2), McKay DL(3), Johnson EJ(3). Author information: (1)The Friedma

Lutein augments the hypoglycemic effect of metformin through the gut microbiota-imidazole propionate axis in type 2 diabetic model mice.

24. Sci Rep. 2025 Aug 27;15(1):31641. doi: 10.1038/s41598-025-16133-y. Lutein augments the hypoglycemic effect of metformin through the gut microbiota-imidazole propionate axis in type 2 diabetic model mice. Liu K(#)(1)(2), Han Y(#)(1)(3), Zhang J(#)(1), Yin Z(4), Yan H(5), Gao W(1), Tong H(1),

Egg white protein-sodium alginate nanoparticle stabilized algal oil Pickering emulsion loaded with lutein: Stability, bioaccessibility, and synergistic anti-inflammation.

27. Int J Biol Macromol. 2025 Jun;317(Pt 1):144809. doi: 10.1016/j.ijbiomac.2025.144809. Epub 2025 May 30. Egg white protein-sodium alginate nanoparticle stabilized algal oil Pickering emulsion loaded with lutein: Stability, bioaccessibility, and synergistic anti-inflammation. Zhan Y(1), Wei H(

Synergistic Action of Membrane-Bound and Water-Soluble Antioxidants in Neuroprotection.

35. Molecules. 2021 Sep 4;26(17):5385. doi: 10.3390/molecules26175385. Synergistic Action of Membrane-Bound and Water-Soluble Antioxidants in Neuroprotection. Polutchko SK(1), Glime GNE(1), Demmig-Adams B(1). Author information: (1)Department of Ecology and Evolutionary Biology, University of Co

Potential health benefits of carotenoid lutein: An updated review.

38. Food Chem Toxicol. 2021 Aug;154:112328. doi: 10.1016/j.fct.2021.112328. Epub 2021 Jun 8. Potential health benefits of carotenoid lutein: An updated review. Mitra S(1), Rauf A(2), Tareq AM(3), Jahan S(3), Emran TB(4), Shahriar TG(1), Dhama K(5), Alhumaydhi FA(6), Aljohani ASM(7), Rebezov M(8)

Potential of Chlorella as a Dietary Supplement to Promote Human Health.

17. Nutrients. 2020 Aug 20;12(9):2524. doi: 10.3390/nu12092524. Potential of Chlorella as a Dietary Supplement to Promote Human Health. Bito T(1), Okumura E(2), Fujishima M(2), Watanabe F(1). Author information: (1)Department of Agricultural, Life and Environmental Sciences, Faculty of Agricultu

Cytoprotective effects of carotenoids-rich extract from Lycium barbarum L. on the beauvericin-induced cytotoxicity on Caco-2 cells.

36. Food Chem Toxicol. 2019 Nov;133:110798. doi: 10.1016/j.fct.2019.110798. Epub 2019 Aug 29. Cytoprotective effects of carotenoids-rich extract from Lycium barbarum L. on the beauvericin-induced cytotoxicity on Caco-2 cells. Juan-García A(1), Montesano D(2), Mañes J(3), Juan C(3). Author infor

Low-dose doxorubicin with carotenoids selectively alters redox status and upregulates oxidative stress-mediated apoptosis in breast cancer cells.

40. Food Chem Toxicol. 2018 Aug;118:675-690. doi: 10.1016/j.fct.2018.06.027. Epub 2018 Jun 18. Low-dose doxorubicin with carotenoids selectively alters redox status and upregulates oxidative stress-mediated apoptosis in breast cancer cells. Vijay K(1), Sowmya PR(1), Arathi BP(1), Shilpa S(1), Sh

Carotenoid Lutein Selectively Inhibits Breast Cancer Cell Growth and Potentiates the Effect of Chemotherapeutic Agents through ROS-Mediated Mechanisms.

31. Molecules. 2018 Apr 14;23(4):905. doi: 10.3390/molecules23040905. Carotenoid Lutein Selectively Inhibits Breast Cancer Cell Growth and Potentiates the Effect of Chemotherapeutic Agents through ROS-Mediated Mechanisms. Gong X(1), Smith JR(2), Swanson HM(3), Rubin LP(4)(5). Author information:

Combination of EPA with Carotenoids and Polyphenol Synergistically Attenuated the Transformation of Microglia to M1 Phenotype Via Inhibition of NF-κB.

37. Neuromolecular Med. 2017 Sep;19(2-3):436-451. doi: 10.1007/s12017-017-8459-5. Epub 2017 Aug 4. Combination of EPA with Carotenoids and Polyphenol Synergistically Attenuated the Transformation of Microglia to M1 Phenotype Via Inhibition of NF-κB. Hadad N(1), Levy R(2). Author information: (1

Astaxanthin from shrimp efficiently modulates oxidative stress and allied cell death progression in MCF-7 cells treated synergistically with β-carotene and lutein from greens.

21. Food Chem Toxicol. 2017 Aug;106(Pt A):58-69. doi: 10.1016/j.fct.2017.05.024. Epub 2017 May 13. Astaxanthin from shrimp efficiently modulates oxidative stress and allied cell death progression in MCF-7 cells treated synergistically with β-carotene and lutein from greens. Sowmya PR(1), Arathi