흰목이버섯 (은이)

Effectiveness of Fish Roe, Snow Fungus, and Yeast Supplementation for Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

1. Nutrients. 2023 Sep 29;15(19):4221. doi: 10.3390/nu15194221. Effectiveness of Fish Roe, Snow Fungus, and Yeast Supplementation for Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Lin YK(1)(2)(3), Lin YH(4), Chiang CF(4), Jingling L(5). Author information: (1

Synergistic immunomodulatory effect of complex polysaccharides from seven herbs and their major active fractions.

2. Int J Biol Macromol. 2020 Dec 15;165(Pt A):530-541. doi: 10.1016/j.ijbiomac.2020.09.199. Epub 2020 Sep 28. Synergistic immunomodulatory effect of complex polysaccharides from seven herbs and their major active fractions. Deng Y(1), Xie J(1), Luo Z(2), Li SP(3), Zhao J(4). Author information:

Effect of Tremella fuciformis on the neurite outgrowth of PC12h cells and the improvement of memory in rats.

3. Biol Pharm Bull. 2007 Apr;30(4):708-14. doi: 10.1248/bpb.30.708. Effect of Tremella fuciformis on the neurite outgrowth of PC12h cells and the improvement of memory in rats. Kim JH(1), Ha HC, Lee MS, Kang JI, Kim HS, Lee SY, Pyun KH, Shim I. Author information: (1)Department of Integrative Me

Efficacy and Safety of Tremella fuciformis in Individuals with Subjective Cognitive Impairment: A Randomized Controlled Trial.

1. J Med Food. 2018 Apr;21(4):400-407. doi: 10.1089/jmf.2017.4063. Epub 2018 Jan 10. Efficacy and Safety of Tremella fuciformis in Individuals with Subjective Cognitive Impairment: A Randomized Controlled Trial. Ban S(1), Lee SL(1), Jeong HS(2), Lim SM(3), Park S(1), Hong YS(3), Kim JE(1). Author information: (1)1 Department of Brain and Cognitive Sciences, Division of Convergence, Scranton College, Ewha Womans University , Seoul, Korea. (2)2 Department of Radiology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea , Seoul, Korea. (3)3 Department of Radiology, School of Medicine, Ewha Womans University , Seoul, Korea. The efficacy and safety of Tremella fuciformis (TF) as a nutritional supplement were assessed in individuals with subjective cognitive impairment (SCI). Seventy-five individuals with SCI were enrolled in an 8-week, randomized, double-blind, placebo-controlled trial of TF (600 mg/day, n = 30 or 1200 mg/day, n = 30) or placebo (n = 15). The primary outcome measure was changes in total scores of the subjective memory complaint questionnaire. The secondary outcome measures were changes in performance on short-term memory and executive functions, which were assessed using standardized cognitive tests. In addition, voxel-based morphometry was performed to examine the effects of TF on changes in gray matter volume. The individuals in the TF group showed greater improvements in the total scores on the subjective memory complaint questionnaire compared with those in the placebo group. There were also significantly greater improvements in short-term memory and executive functions in the TF group relative to the placebo group. Exploratory analysis demonstrated that there were significant group-by-visit interactions on the left precuneus, right supramarginal gyrus, right middle frontal gyrus, and right postcentral gyrus at corrected P < .05. Overall frequency of adverse events did not differ among high-dose TF (40.4%), low-dose TF (35.1%), and placebo groups (41.4%). The current findings suggest that TF could be safely administered to relieve subjective memory complaints and enhance cognition in individuals with SCI. DOI: 10.1089/jmf.2017.4063 PMID: 29319408 [Indexed for MEDLINE]

Tremella fuciformis beverage improves glycated hemoglobin A1c and waist circumference in overweight/obese prediabetic subjects: a randomized controlled trial.

2. BMC Nutr. 2024 Mar 4;10(1):44. doi: 10.1186/s40795-024-00842-0. Tremella fuciformis beverage improves glycated hemoglobin A1c and waist circumference in overweight/obese prediabetic subjects: a randomized controlled trial. Gitsomboon S(1), Ratanapornsompong G(1), Ongphiphadhanakul B(1), Thongpradit S(2), Chanprasertyothin S(2), Chailurtkit LO(1), Nimitphong H(3). Author information: (1)Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6th Road, Ratchathewi, 10400, Bangkok, Thailand. (2)Research Center, Academic Affairs and Innovations, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6th Road, Ratchathewi, 10400, Bangkok, Thailand. (3)Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6th Road, Ratchathewi, 10400, Bangkok, Thailand. hataikarnn@hotmail.com. BACKGROUND: Prediabetes is increasing worldwide. Previous studies have demonstrated the potential of β-glucan derived from oat or barley to lower blood glucose, body weight, and plasma lipid levels. These findings offer a potentially attractive strategy for reducing the risk of diabetes in prediabetic individuals. However, the effects of β-glucan from Tremella fuciformis on glucose metabolism and anthropometric measurements in humans have yet to be studied. We hypothesized that β-glucan from Tremella fuciformis may improve metabolic parameters in subjects with prediabetes. This study aimed to investigate the effects of a once-daily beverage containing Tremella fuciformis (snow mushroom) on anthropometric measurements, metabolic biomarkers, and insulin sensitivity in overweight/obese subjects with prediabetes. METHODS: In this double-blind RCT, 56 participants were randomly assigned to receive either a Tremella fuciformis beverage or placebo daily for 12 weeks. All parameters were assessed at baseline and after the intervention. RESULTS: After 12 weeks, participants in the intervention group exhibited significant improvements in glycated hemoglobin A1c (HbA1C; 6.03 ± 0.26% at baseline vs. 5.96 ± 0.25% at 12 weeks, p = 0.047, Cohen's d = 0.39) and waist circumference (95.2 ± 12.51 cm at baseline vs. 93.46 ± 11.48 cm at 12 weeks, p = 0.022, Cohen's d = 0.45). There were no adverse events reported. CONCLUSION: This exploratory study demonstrated that Tremella fuciformis beverage consumption may improve HbA1C and waist circumference in overweight/obese prediabetic individuals. Further research, including larger-scale RCTs and mechanistic studies, is needed to confirm these findings and optimize the therapeutic potential of Tremella fuciformis derivatives in managing prediabetes and preventing type 2 diabetes. TRIAL REGISTRATION: Registered in Thai Clinical Trials Registry (14/07/2021, TCTR20210714004). © 2024. The Author(s). DOI: 10.1186/s40795-024-00842-0 PMCID: PMC10913275 PMID: 38439104 Conflict of interest statement: The authors declare that they have no known competing financial interests or personal relationships that could have or may have appeared to influence the work reported in this paper.