엽산 (합성)

Spina bifida in Africa: A systematic review and Meta-Analysis of Presentation, Management, and outcomes.

1. J Clin Neurosci. 2026 Jun;148:111986. doi: 10.1016/j.jocn.2026.111986. Epub 2026 Mar 17. Spina bifida in Africa: A systematic review and Meta-Analysis of Presentation, Management, and outcomes. O'Leary S(1), Newsome-Cuby T(2), Odiase P(3), Patel S(4), Khalil ME(5), Pulido S(6), Gowda P(7), Y

Prevalence of Congenital Abnormalities in Abortuses and Stillbirths in India: A Systematic Review and Meta-Analysis.

2. Congenit Anom (Kyoto). 2026 Jan-Dec;66(1):e70050. doi: 10.1002/cga.70050. Prevalence of Congenital Abnormalities in Abortuses and Stillbirths in India: A Systematic Review and Meta-Analysis. Das SS(1), Sharma S(1), Mahajan R(1), Kaushal S(2), Sharma M(3), Singh H(1), Ramkumar M(1). Author in

Complex Effects of B-Vitamin Combinations on Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials over Three Decades.

3. Nutrients. 2026 Mar 5;18(5):842. doi: 10.3390/nu18050842. Complex Effects of B-Vitamin Combinations on Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials over Three Decades. Ren R(1), Yang A(2), Chow A(3), Wang K(4), Wang S(5), Leo C(6), Lu Y(7)(8),

Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.

4. Cochrane Database Syst Rev. 2026 Feb 18;2(2):CD014217. doi: 10.1002/14651858.CD014217.pub2. Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas. Qi YP(1), Crider KS(1), Gutman J(2), Centeno-Tablante E(3)(4), Fot

The effect of prenatal balanced energy and protein supplementation on small vulnerable newborn types in low- and middle-income countries: A systematic review and meta-analysis of individual participant data.

5. PLoS Med. 2026 Feb 17;23(2):e1004716. doi: 10.1371/journal.pmed.1004716. eCollection 2026 Feb. The effect of prenatal balanced energy and protein supplementation on small vulnerable newborn types in low- and middle-income countries: A systematic review and meta-analysis of individual particip

Influencing factors of neural tube malformation: a systematic review and meta-analysis.

6. Afr Health Sci. 2025 Mar;25(1):604-622. doi: 10.4314/ahs.v25i1.45. Influencing factors of neural tube malformation: a systematic review and meta-analysis. Wu X(1), Bian X(1), Zheng Q(1), Gu Y(1), Wang Y(1), Bao T(1), Zhou W(1). Author information: (1)Department 2 of Ultrasonography, Baoding N

Combined B-vitamin supplementation on homocysteine and vascular outcomes in coronary heart disease: a meta-analysis.

7. Ann Med. 2026 Dec;58(1):2622208. doi: 10.1080/07853890.2026.2622208. Epub 2026 Jan 30. Combined B-vitamin supplementation on homocysteine and vascular outcomes in coronary heart disease: a meta-analysis. Guo L(1), Shi X(2), Wang G(3), Han W(1), Ding R(1), Wang S(4), Yuan D(3). Author informa

Oral iron supplements for children in malaria-endemic areas.

8. Cochrane Database Syst Rev. 2026 Jan 9;1(1):CD006589. doi: 10.1002/14651858.CD006589.pub5. Oral iron supplements for children in malaria-endemic areas. Itzkovich M(1)(2), Neuberger A(3), Harris I(4)(5), Yahav D(1)(5), Paul M(3), Gilboa M(5)(6). Author information: (1)Infectious Diseases Unit

Folate Intake and Breast Cancer Risk: A Systematic Review and Meta-Analysis.

9. Mol Nutr Food Res. 2026 Jan;70(1):e70354. doi: 10.1002/mnfr.70354. Folate Intake and Breast Cancer Risk: A Systematic Review and Meta-Analysis. Eleotério MR(1), Ferreira LS(1), Azevedo FM(1), Candido AC(1), Franceschini SDCC(1), de Souza ECG(1). Author information: (1)Department of Nutrition

The effectiveness and safety of the active form of folate on biochemical parameters in women of childbearing age: A systematic review and meta-analysis.

10. Medicine (Baltimore). 2025 Dec 12;104(50):e46564. doi: 10.1097/MD.0000000000046564. The effectiveness and safety of the active form of folate on biochemical parameters in women of childbearing age: A systematic review and meta-analysis. Xie M(1)(2)(3)(4), Qing X(1), Huang H(1), Zhang J(2)(3)

A prospective, randomized, double-blind, placebo-controlled, multicenter study of thiamin plus folic acid in the treatment of cognitive impairment in patients undergoing maintenance hemodialysis.

11. Ren Fail. 2026 Dec;48(1):2658981. doi: 10.1080/0886022X.2026.2658981. Epub 2026 Apr 30. A prospective, randomized, double-blind, placebo-controlled, multicenter study of thiamin plus folic acid in the treatment of cognitive impairment in patients undergoing maintenance hemodialysis. Xie K(1

[Preliminary analysis of mFOLFOXIRI plus bevacizumab combined with cytoreductive surgery for resectable peritoneal metastases from colorectal cancer: a prospective,randomized phase II clinical trial].

12. Zhonghua Wei Chang Wai Ke Za Zhi. 2026 Apr 25;29(4):484-491. doi: 10.3760/cma.j.cn441530-20260110-00026. [Preliminary analysis of mFOLFOXIRI plus bevacizumab combined with cytoreductive surgery for resectable peritoneal metastases from colorectal cancer: a prospective,randomized phase II cli

STRATEGIC-1: multiple-line, randomized, open-label GERCOR-PRODIGE-39 phase III trial in unresectable RAS/BRAF wild-type metastatic colorectal cancer.

13. Signal Transduct Target Ther. 2026 Apr 14;11(1):133. doi: 10.1038/s41392-026-02639-y. STRATEGIC-1: multiple-line, randomized, open-label GERCOR-PRODIGE-39 phase III trial in unresectable RAS/BRAF wild-type metastatic colorectal cancer. Chibaudel B(1), Dourthe LM(2), André T(3), Henriques J(4

Determination of Folate Bioavailability From Brewer's Yeast in a Dual Isotope Randomized Human Intervention Study.

14. Mol Nutr Food Res. 2026 Apr;70(7):e70453. doi: 10.1002/mnfr.70453. Determination of Folate Bioavailability From Brewer's Yeast in a Dual Isotope Randomized Human Intervention Study. Weber N(1), Striegel L(1), Methner Y(2), Brandl B(3), Groehn V(4), Knapp JP(4), Skurk T(3)(5), Rychlik M(1)(6)

Perception and acceptance of micronutrient-Fortified Bouillon among Non-Index Household Members: A longitudinal sub-study nested within a randomized trial in Northern Ghana.

15. PLoS One. 2026 Apr 3;21(4):e0345106. doi: 10.1371/journal.pone.0345106. eCollection 2026. Perception and acceptance of micronutrient-Fortified Bouillon among Non-Index Household Members: A longitudinal sub-study nested within a randomized trial in Northern Ghana. Kyereh FK(1), Ohemeng AN(1)

Second-line liposomal irinotecan plus S-1 vs. liposomal irinotecan plus 5-fluorouracil in metastatic pancreatic cancer: The phase I/II randomized NAPAN trial.

18. Eur J Cancer. 2026 May 15;239:116683. doi: 10.1016/j.ejca.2026.116683. Epub 2026 Mar 20. Second-line liposomal irinotecan plus S-1 vs. liposomal irinotecan plus 5-fluorouracil in metastatic pancreatic cancer: The phase I/II randomized NAPAN trial. Gehrels AM(1), Pijnappel EN(2), van Daalen

Radiofrequency Ablation and Chemotherapy vs Chemotherapy Only in Locally Advanced Pancreatic Cancer: The PELICAN Randomized Clinical Trial.

30. JAMA Netw Open. 2026 Mar 2;9(3):e263861. doi: 10.1001/jamanetworkopen.2026.3861. Radiofrequency Ablation and Chemotherapy vs Chemotherapy Only in Locally Advanced Pancreatic Cancer: The PELICAN Randomized Clinical Trial. Seelen LWF(1)(2), Brada LJH(1)(2), Walma MS(1)(2), Rombouts SJE(1)(2), B

Aflibercept and 5-FU vs. FOLFOX as 1st line treatment for older adults or frail elderly patients with metastatic colorectal cancer - The randomized phase 2 AIO / IKF ELDERLY trial (AIO-KRK-0117 / IKF 629).

35. Eur J Cancer. 2026 May 15;239:116689. doi: 10.1016/j.ejca.2026.116689. Epub 2026 Mar 24. Aflibercept and 5-FU vs. FOLFOX as 1st line treatment for older adults or frail elderly patients with metastatic colorectal cancer - The randomized phase 2 AIO / IKF ELDERLY trial (AIO-KRK-0117 / IKF 629

Randomized phase II study of FOLFIRI plus ramucirumab versus FOLFOXIRI plus ramucirumab as first-line treatment for metastatic colorectal cancer: WJOG9216G (RECAST).

41. Eur J Cancer. 2026 May 2;238:116688. doi: 10.1016/j.ejca.2026.116688. Epub 2026 Mar 19. Randomized phase II study of FOLFIRI plus ramucirumab versus FOLFOXIRI plus ramucirumab as first-line treatment for metastatic colorectal cancer: WJOG9216G (RECAST). Kito Y(1), Yamazaki K(2), Shoji H(3),

Atezolizumab plus FOLFOX for Stage III Mismatch Repair-Deficient Colon Cancer.

28. N Engl J Med. 2026 Mar 26;394(12):1155-1166. doi: 10.1056/NEJMoa2507874. Atezolizumab plus FOLFOX for Stage III Mismatch Repair-Deficient Colon Cancer. Sinicrope FA(1)(2), Ou FS(3), Arnold D(4), Peters WR(5), Behrens RJ(6), Lieu CH(7), Matin K(8), Cohen DJ(9), Potter SL(10), Nixon AB(11), Kot

Tumor-targeted Exosomal Delivery of Celastrol for Enhanced Therapeutic Efficacy in NSCLC.

8. Theranostics. 2026 Mar 3;16(10):5125-5149. doi: 10.7150/thno.125096. eCollection 2026. Tumor-targeted Exosomal Delivery of Celastrol for Enhanced Therapeutic Efficacy in NSCLC. Moholkar DN(1)(2), Kandimalla R(1)(2), Saeed M(3), Arif Y(1), Tyagi N(1), Singhal R(4)(5), Kyakulaga AH(1)(2), Saee

JI-CJ002, a Natural Herbal Formula, Enhances the Antitumor Efficacy of FOLFOX in Colorectal Cancer by Suppressing the DDR Pathway.

19. Anticancer Res. 2025 Nov;45(11):4987-5000. doi: 10.21873/anticanres.17841. JI-CJ002, a Natural Herbal Formula, Enhances the Antitumor Efficacy of FOLFOX in Colorectal Cancer by Suppressing the DDR Pathway. Kim MW(#)(1), Kim D(#)(1), Lee SE(1), Ahn J(1), Park B(1), Cheon C(1)(2)(3), Ko SG(4)(

Synergistic alleviation of obesity and associated cardiovascular complications by combined modulation of FASN/Arginase/eNOS uncoupling.

50. Biomed Pharmacother. 2025 Oct;191:118486. doi: 10.1016/j.biopha.2025.118486. Epub 2025 Aug 28. Synergistic alleviation of obesity and associated cardiovascular complications by combined modulation of FASN/Arginase/eNOS uncoupling. Sabry EA(1), Elbatreek MH(2), El-Basossy HM(3), Hassan NA(4).

Contribution of Organic Anion Transporter 3 in Delayed Elimination of Methotrexate by Concomitant Administration of Febuxostat.

38. Biopharm Drug Dispos. 2025 Aug;46(4):165-171. doi: 10.1002/bdd.70014. Epub 2025 Aug 25. Contribution of Organic Anion Transporter 3 in Delayed Elimination of Methotrexate by Concomitant Administration of Febuxostat. Ikemura K(1)(2), Kobayashi S(3), Wang D(2), Okuda M(1)(2). Author informati

Carrier-Free Nanomedicine Based on Celastrol and Methotrexate for Synergistic Treatment of Breast Cancer via Folate Targeting.

18. Int J Nanomedicine. 2025 Jun 27;20:8291-8304. doi: 10.2147/IJN.S516921. eCollection 2025. Carrier-Free Nanomedicine Based on Celastrol and Methotrexate for Synergistic Treatment of Breast Cancer via Folate Targeting. Li X(1), Zhang M(1), Wang X(1), Ma P(2), Song Y(1). Author information: (1

Synergetic effects of Ulva lactuca and Pterocladiella capillacea on the multidrug-resistant Klebsiella pneumoniae.

32. BMC Microbiol. 2025 Jun 26;25(1):370. doi: 10.1186/s12866-025-04102-4. Synergetic effects of Ulva lactuca and Pterocladiella capillacea on the multidrug-resistant Klebsiella pneumoniae. Mahmoud RM(1), Khedr GM(2), Taha RM(2), Adawy AA(2). Author information: (1)Botany Department, Faculty of

Molecular Dynamics Simulations of Plasma-Antifolate Drug Synergy in Cancer Therapy.

33. Biomolecules. 2025 May 27;15(6):773. doi: 10.3390/biom15060773. Molecular Dynamics Simulations of Plasma-Antifolate Drug Synergy in Cancer Therapy. Niu Y(1), Zhao T(1), Wang X(1), Sun Y(1), Zhang Y(1). Author information: (1)School of Electrical Engineering, Shandong University, Ji'nan 25006

Perturbation of Pseudomonas aeruginosa peptidoglycan recycling by anti-folates and design of a dual-action inhibitor.

32. mBio. 2025 Mar 12;16(3):e0298424. doi: 10.1128/mbio.02984-24. Epub 2025 Jan 29. Perturbation of Pseudomonas aeruginosa peptidoglycan recycling by anti-folates and design of a dual-action inhibitor. Yaeger LN(1)(2), Sychantha D(1)(2), Luong P(1)(2), Shekarriz S(1)(2), Goncalves O(3), Dobrin A

Synergistically effects of n-3 PUFA and B vitamins prevent diabetic cognitive dysfunction through promoting TET2-mediated active DNA demethylation.

9. Clin Nutr. 2025 Feb;45:111-123. doi: 10.1016/j.clnu.2025.01.002. Epub 2025 Jan 6. Synergistically effects of n-3 PUFA and B vitamins prevent diabetic cognitive dysfunction through promoting TET2-mediated active DNA demethylation. Chen L(1), Liu R(2), He X(3), Fang J(2), Zhou L(2), Qi Z(2), Ta

Green Tea Catechins as Perpetrators of Drug Pharmacokinetic Interactions.

7. Clin Pharmacol Ther. 2025 Jul;118(1):45-61. doi: 10.1002/cpt.3547. Epub 2025 Jan 2. Green Tea Catechins as Perpetrators of Drug Pharmacokinetic Interactions. Kyriacou NM(1), Gross AS(1), McLachlan AJ(1). Author information: (1)Sydney Pharmacy School, Faculty of Medicine and Health, University